BioMarin Pharmaceutical Inc.
Asset Team Lead Palenziq and PKU
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Who We Are
BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions.
Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions.
Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world.
About Commercial
Be part of the worldwide infrastructure that gets our drugs to underserved patients around the world. Our global sales force solidifies BioMarin’s commercial presence in the United States and Europe and is rapidly growing in other regions, such as South America, EuMEA, and Asia-Pacific.
Asset Team Lead Palynziq and PKU
Location: London (hybrid 2 days per week onsite)
Closing date: 4 August 2026
Role
Asset Team Lead (ATL) Palynziq and PKU
Overview Description
Serves as the single point of accountability for end-to-end asset success. Primary liaison with executive management and the ET Business Unit on the asset strategy and has overall accountability to executive management for the integrated asset strategy. Acts as the asset champion and leads the cross-functional team of functional leaders that together develop and execute the integrated asset strategy. Expected to drive decision-making forward, facilitate cross-functional collaboration, and ensure that the asset strategy aligns with BioMarin’s enterprise goals.
Commits to developing and facilitating the strategic conversations that advance the asset—both within the Asset Team and across the organization. Leads with urgency towards the attainment of key milestones and adherence to the path that optimally balances risk and value creation. Commits to establishing a culture of inclusivity and collaboration—and to proactively facilitating and integrating the cross-functional dialogue needed to develop the integrated asset strategy and compelling recommendations that will enable confident executive-level decision-making. Does so in a way that is optimal and objective, critically analyzing strengths, weaknesses, opportunities, and threats.
Key Responsibilities
Strategic Planning
- Ensures the integrated asset strategy is closely connected to ET Business Unit priorities, commercial objectives, and portfolio trade-offs.
- Leads the development and execution of the integrated asset strategy, ensuring alignment with BioMarin’s enterprise objectives, to maximize an asset’s potential for patients and value proposition for BioMarin.
- Shapes the strategy across the asset lifecycle, from development to commercialization & the lifecycle post initial launch (e.g., next-generation products).
- Drives critical decision-making by proactively communicating strategic challenges and opportunities as new relevant information emerges.
- Ensures integrated stage gate plans are aligned with the integrated asset strategy and ensures assumptions and drivers are aligned with plans to inform financial planning.
- Sets aspirational goals for timelines and budget.
- Partners with functional leaders to ensure appropriate resource allocation to accomplish goals.
- Provides continuity of leadership across key transitions and decision points throughout the asset lifecycle.
- Ensure potential risks/trade-offs are identified and contingency planning with a solutions’ focused mindset.
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Operational Execution
- Partners with the ET Business Unit to ensure execution plans reflect business priorities, market realities, and lifecycle value opportunities.
- Embeds an asset-first mindset into daily operations to define priorities and resource allocation in collaboration with functional leaders.
- Represents the asset in Governance, Portfolio Reviews, and ET Business Unit discussions.
- Supports critical deliverables to maximize the value of the asset, including clinical study strategy and design, LCM prioritization of potential indications and combinations, formulation and delivery mechanism strategy, regulatory strategy, treatment landscape and patient journey assessment, Target Product Profile (especially in relation to asset therapies in the market), and global launch strategy, inclusive of market sequencing.
- Engages the right partners and external stakeholders by being the voice of the asset to the external world.
- With support from Pipeline Commercialization Strategy (PCS) and Competitive Intelligence (CI), aligns early development to ensure commercial viability or drives decision to stop development of the asset.
- Resolves business and technical challenges (e.g., formulation/CMC optimization) in partnership with key SMEs.
- Directs KPIs and goal setting for the Asset Team as a whole.
- Ensures that Asset Team acts with a sense of urgency in the execution of the Integrated Asset Strategy, including timely and effective decision-making through Asset Team or through functional leaders or executive management/Governance, as appropriate.
- Ensures alignment of asset strategy/plan/execution with management expectations and priorities.
- Leads team in developing Strategic Deliverables to support the Integrated Asset Strategy.
- Primary source for information as needed for external communications (press releases, investor related, etc.).
- Reviews health authority-related documents and ensures consistency with strategic objectives for the program.
Team Effectiveness
- Creates effective connectivity between the Asset Team and the ET Business Unit to ensure transparency, alignment, and timely escalation of business-critical decisions.
- Fosters a collaborative cross-functional environment to ensure a high-functioning and high-performing Asset Team.
- Works closely with Program Management and functional leads to ensure Strategic Deliverables necessary to inform IAS are funded, initiated, tracked, and completed on time.
- Ensures cross functional partnerships and resources are leveraged effectively, and with accountability, to achieve program objectives.
- Drives collaboration and transparency across all functions on the Asset Team and challenges team members to be broad and inclusive in their strategy planning.
- Resolves conflicts at the Asset Team, provide and receive feedback to develop and maintain a high performing team.
- Builds 1:1 relationships to establish trust, open communication channels, and improve productivity.
- Weighs in on Asset Team member performance management.
Skills And Capabilities
Leadership
- Is capable of driving development of the asset without having direct authority over the functional-level activities necessary to do so.
- Provides the vision for and clearly articulates the Asset Strategy and brings the cross-functional teams together to align and plan for execution.
- Progresses the Asset Strategy forward and provides strategic direction, including prioritizing what’s important to the Asset.
- Actively pursues the path to value creation by driving what is on the critical path for the next key milestone.
- Is able to adapt and disrupt to push the leading edge of asset development.
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Enterprise-Level Thinking and Decision Making
- Understands how asset-level choices affect broader ET Business Unit strategy, financial performance, and portfolio priorities.
- Applies a comprehensive, strategic, and forward-looking approach to decision-making that incorporates both short- and long-term implications, the organization as a whole, the interests of key customer groups, and the needs of the patients we serve.
- Seeks to understand the interconnectedness and interdependencies of different functions and processes critical to the development of the asset.
Influence and Collaboration
- Drives open dialogue, debate, and discussion, including participation in strategic discussions within the team and within BioMarin’s leadership.
- Is an exceptional listener with a willingness to understand and an ability to challenge and influence the perspectives of other Asset Team members, functional colleagues, and leadership.
Communication and Organizational Navigation
- Communicates asset strategy, risks, trade-offs, and decisions clearly to Asset Team members, functional leaders, executive management, and the Metabolic Business Unit.
- Is the voice of the Asset during development. Communicates to team members, function leaders, and management.
- Identifies key stakeholders for inputs, aligning points of view, identifying risks and barriers, solving problems, clarifying ambiguity, and facilitating decision making.
Functional Experience and Expertise
- Possesses a strong understanding of new product development as well as product lifecycle management.
- Possesses a relevant understanding of functional-level needs, objectives, and processes—and can identify functional-level issues that have cross-functional implications.
- Foundational understanding of finance and business principles.
Background and Experience
Background/Experience
- At least 10 years of industry experience.
- At least 5 years of experience working on or leading matrixed, cross-functional teams.
- May come from a clinical science/R&D or Commercial background.
- Respected problem-solving leader who can resolve both business and technical challenges.
Specific Job Skills
- Strong leadership skills to drive success in a cross-functional team.
- Strategic thinking to plan for the long-term success of an asset, not just hitting today’s targets.
Mindsets
- Data-driven decision making to steer asset strategy based on evidence.
- Hardworking, selfless, and humble.
- Patient centric.
- Proud of their craft and inspired by what they're called on to achieve.
Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.
Equal Opportunity Employer/Veterans/Disabled
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be
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