Flagship Pioneering
Associate Director, Head of High Throughput Lab
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Position Summary:
Quotient is seeking an experienced Associate Director, Head of High Throughput Laboratory to lead and continuously develop the high-throughput laboratory supporting our somatic genomics platform. This is a pivotal leadership role within a rapidly growing biotechnology company, responsible for delivering high-quality, reproducible multi-omic data across Quotient's disease portfolio. Reporting to the Head of Research Strategy & Operations, the incumbent will lead multidisciplinary teams spanning histology, flow cytometry, molecular biology and scientific management, ensuring laboratory delivery remains aligned with research priorities while building a high-performing, scalable function. Working in close partnership with scientific leadership, assay development, automation and research project management, you will translate research priorities into efficient laboratory execution, embedding operational excellence, scientific quality and continuous improvement.
Responsibilities:
- Lead, develop and inspire a multidisciplinary team of Scientific Managers, Subject Matter Experts and Research Associates, fostering a high-performing, collaborative and accountable culture
- Translate company strategy and portfolio priorities into clear laboratory delivery plans, ensuring the High Throughput Laboratory consistently delivers high-quality, reproducible scientific data safely, efficiently and to agreed project milestones while maintaining the highest standards of health and safety, regulatory compliance and data integrity
- Provide operational leadership across Histology, Flow Cytometry, Molecular Biology and Scientific Sample Management, ensuring laboratory capacity, capability and resource planning support both current and future portfolio demands
- Partner closely with Research Project Management, Scientific Leadership, Assay Development and Automation to align laboratory execution with integrated project plans, operational priorities and future platform requirements
- Develop, implement and continuously improve scalable laboratory systems, workflows and operational best practices that increase laboratory quality, efficiency, throughput and reproducibility
- Develop and monitor laboratory performance metrics and KPIs, using data to drive operational performance, capacity planning and continuous improvement across the High Throughput Laboratory
- Identify opportunities for strategic investment in laboratory infrastructure, equipment, staffing and technology to ensure laboratory capability evolves alongside Quotient's research portfolio
- Develop organisational capability through succession planning, workforce development, coaching and creation of clear career pathways, ensuring Scientific Managers and Subject Matter Experts continue to grow as future organisational leaders
- Build strong collaborative relationships across Research, Data Science and AI, Assay Development, Laboratory Operations, Project Management and external partners, representing the High Throughput Laboratory in organisational planning, governance and strategic discussions
- Foster a culture of continuous improvement and psychological safety, empowering teams to challenge constructively, embrace innovation and continuously improve the way science is delivered
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Qualifications:
Essential
- MSc or PhD in Biology or a related scientific discipline with significant post-academic biotechnology experience
- Significant experience leading and developing multidisciplinary laboratory teams
- Proven experience operating and scaling high-throughput laboratory environments
- Strong understanding of genomics and multi-omics workflows and high-throughput laboratory operations
- Demonstrated success implementing operational improvements that increase quality, efficiency and scalability
- Experience balancing day-to-day laboratory delivery with long-term capability development
- Excellent understanding of laboratory health & safety, quality systems and regulatory compliance
- Outstanding people leadership, coaching and organisational development skills
Desirable
- Experience supporting genomics-based drug target identification and early discovery research
- Experience working collaboratively with laboratory automation teams to implement workflow improvements and new technologies
- Experience working within rapidly scaling biotechnology organisations
- Experience supporting matrix organisations delivering multiple concurrent research programs
- Experience embedding operational excellence methodologies into working teams
Values and Behaviors:
- Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence
- Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source
- Recognize the impact of your behavior, language and attitudes, and strive for balanced, meaningful exchanges that enhance mutual growth and understanding in all interactions
- Use a company-first mindset to guide decision-making; prioritize team over individual success
- Take calculated risks and challenge convention in the quest for exceptional outcomes
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About Quotient:
Quotient Therapeutics is a privately-held, early stage company developing breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs.
The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS).
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
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