T-Cypher Bio
Associate Scientist, Protein Engineering, Bispecific team
How your CV stacks up
Upload your CV to see how well it fits this job role
?%
About T-Cypher Bio
T-Cypher Bio is an early-stage, innovative biotechnology company aiming to unlock an expansive target space to build a pipeline of novel, T-cell receptor (TCR)-based therapeutics.
What You Will Do
The primary focus of this role will be to execute experiments relating to the screening & characterisation of soluble TCR proteins that are part of our therapeutic pipeline. The ideal candidate should have a solid understanding of molecular biology and soluble protein production, and be familiar with standard molecular biology software and databases.
Key Responsibilities
- Clone constructs for protein expression, using a range of molecular biology techniques
- Produce soluble TCR proteins using high-throughput protein expression systems and purification methods
- Characterise TCR proteins using various biochemical and biophysical techniques such as SDS-PAGE, HPLC, and differential scanning fluorimetry (DSF)
- Contribute to group and project meetings, offering insights to advance research projects
- Prioritisation of personal workloads and coordination of scientific workstreams and processes
- Analyse and record experimental results and communicate findings to the team and to management
- Maintain and implement good laboratory practices, including accurate laboratory notebook systems, instrument and reagent maintenance, and personnel safety precautions
Reasons to use Rodeo
Start with a chat, not a search bar
Grad scheme, placement, apprenticeship? Not sure what you want yet — that's fine. Your agent talks it through with you and turns "I have no idea" into a shortlist.
It searches the market for you
Every day your agent scans the market matching roles against what actually matters to you, not just keywords on a CV.
Only hits
No noise. No "maybe this fits." Just roles with a clear explanation of why they're right — and where to focus when applying.
To be Successful You Will Need
- BSc or MSc in Biochemistry, Cell or Molecular Biology, Molecular Immunology, or a related discipline with relevant hands-on experience within industry or academia
- Hands-on experience in molecular biology techniques, including PCR, DNA assembly methods (e.g. HiFi), agarose gel electrophoresis, bacterial transformation and culture, DNA preparation (miniprep and midiprep scale), DNA quantification by Nanodrop or fluorescence-based methods (e.g. Qubit), and bead cleanup protocols
- Proficient in expression of soluble recombinant proteins in mammalian cells (e.g. CHO, HEK), and purification by affinity capture methods
- Expertise in biochemical techniques for protein characterisation e.g. SDS-PAGE gel analysis, HPLC, western blot and DSF
- Analysing & presenting results in a concise and accurate manner to the wider team
- Ability to adapt to multiple roles in a matrixed, fast-paced and evolving company
- Enjoy working towards challenging goals in a fast-moving environment
- Ability to follow protocols and SOPs
- Knowledge of health and safety regulations in a laboratory environment
- Strong organisational and communication skills (both written and verbal)
Get help with your application
Your very own career expert that helps elevate your application to the next level.
What We Offer
- Competitive salary and benefits commensurate with qualifications and experience
- Modern, well-equipped office and laboratory facilities on Abingdon Science Park
- Training and development opportunities in line with the company’s goals and growth plans
- An exciting opportunity to help establish an early-stage biotech with ambitions to impact patients’ lives
How to Apply
Applications will be evaluated in the order that they are received, you are encouraged to apply as soon as possible. Applications will close once the position is filled.
“It took my CV and asked me questions relevant to understanding what kind of jobs to suggest for me. Suggestions were almost perfect. Jobs were exactly what I’ve been looking for.”
Jessica, London
Skills