Biomarker Expert Leader Ophthalmology

In this role, you will be accountable for the development and implementation of end-to-end translational biomarker strategies during the preclinical and clinical phases of drug development programs.

• You will lead biomarker-related activities aimed at quantifying drug response and selecting patients for personalized healthcare, acting as Matrix Leader of the BioX (Bioanalytical, Biosample and Biomarker) Expert Team.
• You will assume accountability for research collaborations designed to benefit multiple programs, in line with the relevant project and disease area strategies.
• You will be an active member of preclinical and clinical drug development and project teams.
• You will provide scientific and strategic input into the overall drug and clinical development plans and ensure that biomarker-related activities are fit for purpose and support decision-making within the context of the preclinical and clinical development strategy.
• You will collaborate with academic, industry, internal and external experts, as well as service providers, on biomarker, experimental medicine and natural history studies to identify and evaluate disease biomarkers and novel clinical trial endpoints.

Who you are

• You hold a PhD and/or MD degree and have at least 7 years of well-documented experience in a research, industry or clinical setting. This experience should include at least 3 years of biomarker-related work in the context of drug development, preferably involving protein, metabolite, genetic, imaging or functional biomarkers.
• You are able to lead cross-functional matrix teams, drive team decisions and project needs, and prioritize your work to achieve both individual goals and team deliverables.
• You have a good understanding of methodological and bioanalytical approaches and are able to generate, integrate and interpret preclinical, clinical and drug development data to enable proof of biology, dose selection, patient selection and safety across clinical programs.
• You are a proactive team player who integrates easily into a global organization. You have strong networking skills, are capable of working independently, and enjoy contributing to a collaborative environment where success is driven by the team rather than by individual heroes.
• You have strong presentation and communication skills and are fluent in English.
• You are an innovative and strategic thinker who sees the big picture. You are goal-oriented, have a strong drive and analytical mindset, and are motivated to achieve excellence. You are also able to distill complex topics, develop solutions and articulate them clearly.
• Prior experience in Ophthalmology would be a valuable asset. Experience with omics data interpretation, ocular imaging or functional readouts would be an additional advantage.

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.