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ICON plc

Clinical Data Manager

Johannesburg
Posted about 14 hours ago
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Clinical Data Manager (ICON Job Title: Clinical Data Science Lead)

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

About the Role

As a Clinical Data Manager within ICON Strategic Solutions, you will be dedicated to one of our global pharmaceutical partners, working within a collaborative client-dedicated model. You will play a key role in delivering accurate, reliable, and inspection-ready clinical data that supports the development of innovative therapies for patients worldwide.

This is a hands-on opportunity for an experienced Clinical Data Manager who enjoys study ownership, data review, vendor collaboration and driving data quality from study start-up through database lock and close-out.

What You Will Be Doing

  • Lead or co-lead data management activities across assigned studies from start-up through close-out.
  • Perform EDC data review, data cleaning, query management and reconciliation of external data sources.
  • Create and maintain study documentation, including Data Management Plans, Data Review Plans, eCRF Completion Guidelines and Edit Check Specifications.
  • Conduct EDC and data validation listing UAT and support database lock readiness.
  • Partner with study teams and vendors to resolve data issues, including eCOA, PK, biomarker, local laboratory and safety data discrepancies.
  • Support SAE and protocol deviation reconciliation, issue log maintenance, metrics reporting and eTMF filing.

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I’m in my final year doing Economics and I don’t know whether to apply for grad schemes now or do a masters first. What do you think?

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Graduate Consultant — 2026 Scheme

PwC·London, UK
£35,000/yr

Why you're a good match

Strong

Your economics background and your summer at a regional bank line up with what PwC looks for on the consulting scheme. Applications close in four weeks.

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Why you're a good match

You’ve got the grades and the economics background, and your bank internship is exactly the experience this scheme looks for. Apply soon — deadlines close within the month.

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Strong

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Your summer at the bank plus your econometrics coursework map directly to the day-one responsibilities on this scheme — client modelling, market briefings, and deal support.

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You will have/be

  • Bachelor's degree in a Life Sciences related discipline.
  • 5+ years of Clinical Data Management experience within a CRO, pharmaceutical or biotechnology environment.
  • Experience leading or co-leading studies from start-up through database lock and close-out.
  • Strong hands-on EDC review, data cleaning, query management, external data reconciliation and UAT experience.
  • Clear communication skills and the ability to work independently within fast-paced global study teams.
  • Veeva EDC experience is desirable but not essential.

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Employment with ICON

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Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply.

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Skills

Clinical Data Management
EDC
Data cleaning
Query management
Data reconciliation
UAT
Study start-up
Database lock
Data review
Veeva EDC
Clinical research
Protocol deviation reconciliation
eTMF
Communication skills

Location

Warsaw, Masovian Voivodeship, Poland

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