ICON plc
Clinical Trial Manager

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Clinical Trial Manager - Oncology
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients, and suppliers.
Clinical Trial Manager - Oncology (Late Development)
Location: Home-based, UK
At ICON, our people drive innovation and help shape the future of clinical development. As a Clinical Trial Manager within our client's Late Development Oncology team, you will play a critical role in leading the operational delivery of global clinical studies, ensuring the successful execution of complex oncology programmes while maintaining the highest standards of quality, compliance, and patient safety.
This is an opportunity to join a high-performing team and contribute to cutting-edge oncology research that supports the development of life-changing therapies for patients worldwide.
What You Will Do
As a Clinical Trial Manager, you will provide operational leadership across all phases of study delivery, collaborating with internal and external stakeholders to ensure clinical trials are executed efficiently, on time, and in compliance with all applicable regulations and quality standards.
Key responsibilities include:
- Lead the planning, execution, and oversight of clinical trial activities, ensuring delivery against timelines, budgets, and key study milestones.
- Partner with cross-functional teams to develop and implement study-specific operational plans, processes, and procedures.
- Build and maintain strong relationships with investigators, study sites, vendors, and key stakeholders to support successful study outcomes.
- Monitor study progress, proactively identify risks, and implement mitigation strategies to ensure continued operational excellence.
- Ensure studies are conducted in accordance with ICH-GCP guidelines, protocol requirements, and all applicable local and international regulatory standards.
- Oversee vendor performance and contribute to vendor selection, management, and governance activities where appropriate.
- Drive issue resolution and support critical decision-making related to study conduct, quality, and operational delivery.
- Act as a key point of contact for internal and external stakeholders, providing regular updates on study progress, risks, and achievements.
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About You
You are an experienced Clinical Trial Manager with a proven track record of successfully delivering oncology clinical studies in a commercial clinical research environment. You combine strong operational expertise with excellent stakeholder management skills and the ability to navigate competing priorities in a fast-paced setting.
To be successful in this role, you will bring:
- A degree in Life Sciences, Medicine, Pharmacy, Nursing, or a related scientific discipline, or an equivalent combination of education and relevant experience.
- Demonstrated experience leading the operational delivery of clinical trials and driving study outcomes against key performance indicators.
- Strong understanding of clinical trial regulations, ICH-GCP requirements, and industry best practices.
- Experience working within a commercial pharmaceutical, biotechnology, or CRO environment.
- Prior clinical monitoring experience is advantageous.
- Significant experience managing Oncology clinical trials, ideally within late-phase development programmes.
- Excellent communication, organisational, and problem-solving skills, with the ability to influence and collaborate across diverse stakeholder groups.


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Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance-related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply.
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