ICON Strategic Solutions
Clinical Trial Manager

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Clinical Trial Manager - Oncology
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
Clinical Trial Manager - Oncology (Late Development)
Location: Home-based, UK
At ICON, our people drive innovation and help shape the future of clinical development. As a Clinical Trial Manager within our client's Late Development Oncology team, you will play a critical role in leading the operational delivery of global clinical studies, ensuring the successful execution of complex oncology programmes while maintaining the highest standards of quality, compliance, and patient safety.
This is an opportunity to join a high-performing team and contribute to cutting-edge oncology research that supports the development of life-changing therapies for patients worldwide.
What You Will Do
As a Clinical Trial Manager, you will provide operational leadership across all phases of study delivery, collaborating with internal and external stakeholders to ensure clinical trials are executed efficiently, on time, and in compliance with all applicable regulations and quality standards.
Key Responsibilities Include
- Lead the planning, execution, and oversight of clinical trial activities, ensuring delivery against timelines, budgets, and key study milestones.
- Partner with cross-functional teams to develop and implement study-specific operational plans, processes, and procedures.
- Build and maintain strong relationships with investigators, study sites, vendors, and key stakeholders to support successful study outcomes.
- Monitor study progress, proactively identify risks, and implement mitigation strategies to ensure continued operational excellence.
- Ensure studies are conducted in accordance with ICH-GCP guidelines, protocol requirements, and all applicable local and international regulatory standards.
- Oversee vendor performance and contribute to vendor selection, management, and governance activities where appropriate.
- Drive issue resolution and support critical decision-making related to study conduct, quality, and operational delivery.
- Act as a key point of contact for internal and external stakeholders, providing regular updates on study progress, risks, and achievements.
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About You
You are an experienced Clinical Trial Manager with a proven track record of successfully delivering oncology clinical studies in a commercial clinical research environment. You combine strong operational expertise with excellent stakeholder management skills and the ability to navigate competing priorities in a fast-paced setting.
To Be Successful In This Role, You Will Bring
- A degree in Life Sciences, Medicine, Pharmacy, Nursing, or a related scientific discipline, or an equivalent combination of education and relevant experience.
- Demonstrated experience leading the operational delivery of clinical trials and driving study outcomes against key performance indicators.
- Strong understanding of clinical trial regulations, ICH-GCP requirements, and industry best practices.
- Experience working within a commercial pharmaceutical, biotechnology, or CRO environment.
- Prior clinical monitoring experience is advantageous.
- Significant experience managing Oncology clinical trials, ideally within late-phase development programmes.
- Excellent communication, organisational, and problem-solving skills, with the ability to influence and collaborate across diverse stakeholder groups.
What ICON Can Offer You
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.


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Our Benefits Examples Include
- Various annual leave entitlements
- A range of health insurance offerings to suit you and your family’s needs.
- Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
- Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
- Life assurance
- Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply
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