Oxford Nanopore Technologies
Direct Tax Compliance & Reporting Manager

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Direct Tax Compliance & Reporting Manager
Oxford Nanopore Technologies | Oxford, UK | Hybrid Working (3 days onsite)
About Oxford Nanopore Technologies
At Oxford Nanopore Technologies, our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere.
We have developed a pioneering nanopore-based sensing technology that delivers faster, richer, more accessible and affordable molecular analysis. While the first application of our technology is DNA and RNA sequencing, we continue to advance its use across a wide range of molecules, including proteins.
Our technology is helping researchers and organisations around the world better understand human biology, cancer, infectious diseases, agriculture, environmental ecosystems and much more. Headquartered in the UK, Oxford Nanopore serves customers in more than 125 countries and continues to drive innovation on a global scale.
The Opportunity
We are looking for a Direct Tax Compliance & Reporting Manager to join our growing Tax team in Oxford.
Reporting to the Tax Director, this is a hands-on and varied role within a fast-growing, listed international business. You will take ownership of corporation tax compliance and reporting activities across the Group, while also supporting transfer pricing, tax projects and process improvement initiatives.
This position would suit a qualified accountant or tax professional with a strong grounding in tax accounting and compliance, ideally gained within a multinational or in-house environment. Alongside technical expertise, you'll bring strong organisational skills, commercial awareness and a proactive approach to driving continuous improvement.
Hybrid working available with a minimum expectation of three days per week in our Oxford office.
What You'll Be Doing
- Manage outsourced corporation tax compliance processes across the UK and international group entities, ensuring filings and payments are accurate and submitted on time.
- Coordinate with finance teams, external advisers and stakeholders to gather information and support tax compliance requirements.
- Lead tax reporting activities for interim and year-end group reporting cycles, including preparation of tax disclosures and supporting documentation.
- Manage the Group's transfer pricing compliance, including master and local file requirements and transfer pricing calculations.
- Identify and implement process improvements, leveraging technology and automation where appropriate.
- Support monthly tax reporting activities, including reconciliations, journals and tax-related presentations.
- Oversee tax administration activities, including adviser management, budgets, accruals, purchase orders and tax authority correspondence.
- Prepare and manage tax-related forms and returns, such as certificates of residence and withholding tax filings.
- Contribute to a variety of tax projects covering areas such as global expansion, patent box, transfer pricing and tax efficiency initiatives.
- Support tax enquiries and ensure the business remains up to date with relevant tax legislation and developments.
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About You
We're looking for someone who can combine strong technical expertise with a collaborative and solutions-focused mindset.
You will have:
- ACA, ACCA, CA, CTA or equivalent qualification.
- At least 3 years' post-qualified tax experience.
- Strong knowledge of corporation tax compliance and tax accounting.
- A solid understanding of double-entry bookkeeping principles.
- Excellent attention to detail and a high level of accuracy.
- Strong organisational and project management skills.
- The ability to manage multiple priorities and meet deadlines in a fast-paced environment.
- A proactive, improvement-focused approach and a genuine desire to create efficiencies.
- Excellent written and verbal communication skills.
- Strong Excel skills and confidence working with Microsoft Office applications.
- A collaborative style with the ability to build relationships across teams.
Desirable Experience
- In-house tax experience.
- Experience working within a listed or multinational organisation.
- Experience with D365 or similar ERP systems.
- An interest in tax technology, automation and process optimisation.
- Experience within, or an interest in, the biotechnology or life sciences sector.


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In return
We offer a competitive benefits package including an attractive bonus, generous pension contributions and private healthcare, alongside flexible working and the opportunity to develop your career in a listed, international business with a meaningful purpose. Our Oxford office is set within landscaped surroundings, with tree-lined walks, water features and a lake, creating a welcoming and enjoyable working environment.
If you are motivated by applying your tax expertise in a collaborative team and contributing to work that has real-world impact, we would be delighted to hear from you.
Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.
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Oxford Nanopore Technologies: Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis. The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins. The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments. With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.
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