Key Roles and Responsibilities:

• Act as the frontline DMPK discipline contact, providing leadership and influence in the design of successful DMPK, PKPD, modelling and progression strategies for multiple drug discovery projects.
• Lead DMPK strategy from hit finding and lead optimisation through to candidate selection, nomination and IND-enabling activities.
• Work collaboratively within cross-disciplinary matrix teams and with client partners to support the design, identification and optimisation of candidate molecules.
• Develop and present scientific plans, strategies, results and achievements to external partners, internal stakeholders and senior management.
• Support new business opportunities by defining strategic DMPK requirements and contributing to proposals and client discussions.
• Interpret and integrate data across disciplines to guide project decisions, including the optimisation of ADME and PK properties, DDI assessments, formulation recommendations and PKPD or PBPK modelling.
• Ensure robust human PK and dose predictions throughout the project lifecycle to guide programme direction and assess clinical potential.
• Provide scientific leadership and expert technical direction across the department, applying innovation to scientific problem-solving and the enhancement of Pharmaron’s DMPK services.
• Supervise and mentor DMPK colleagues, supporting their scientific and professional development.

Requirements:

• PhD or equivalent experience in a relevant scientific discipline, such as pharmacology or pharmaceutical sciences.
• Significant experience working on DMPK drug discovery and development projects, with a strong track record of scientific delivery.
• In-depth understanding of mechanistic DMPK and ADME science, with knowledge of related drug discovery disciplines.
• Multi- year experience working within multidisciplinary matrix teams and leading DMPK strategy across integrated projects and through milestones.
• Expertise in scientific problem-solving and the interpretation of complex DMPK and ADME data.
• Excellent written and verbal communication skills, with the ability to influence internal and external stakeholders.
• Experience of supervising or mentoring scientific colleagues.
• Experience of working across multiple modalities and /or experience in modelling and simulation would be advantageous.

Why Join Pharmaron?

This is not simply an opportunity to inherit an established function. It is an opportunity to build, shape and lead a business with significant strategic potential.

You will have the chance to:

• Directly influence a diverse portfolio of drug discovery programmes across different therapeutic areas and scientific approaches.
• Work closely with biotechnology and pharmaceutical partners to solve complex scientific challenges and accelerate innovative medicines towards the clinic.
• Shape your career within a global organisation committed to scientific excellence, innovation and continued capability development.
• Join an expanding and collaborative team that supports one another and places excellence at the heart of everything it does.

Apply Now

If you are an accomplished DMPK leader with the scientific credibility, entrepreneurial mindset and commercial insight to help build a differentiated drug discovery business, we would welcome the opportunity to hear from you.

Join Pharmaron and help shape the next generation of Drug Discovery.

Package Highlights Include:

• Annual performance-related bonus.
• Pension scheme with employer contribution.
• Option for private medical insurance scheme.
• Life assurance and income protection benefits.
• Generous annual leave entitlement (with options to purchase additional days and transfer remaining days to following year*), plus public holidays.
• Employee Assistance Programme.
• Professional membership support and continuous learning opportunities.
• Access to Pharmaron's global scientific network and career development pathways.

Collaborative Culture

Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.