BioNTech
Director Health Economics & Outcomes Research (HEOR)
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London, United Kingdom; Cambridge, US; Gaithersburg, US; Mainz, Germany; New Jersey, US | full time | Job ID: 11271
About the role:
As the Global HEOR Director, you will be at the forefront of advancing BioNTech’s mission by driving impactful health economics and outcomes research strategies. In this role, you will shape value evidence-based approaches that contribute to global market access and reimbursement success, ensuring patients worldwide benefit from our innovative therapies. You’ll collaborate with cross-functional teams in a dynamic environment that values scientific rigor and methodological advancements.
Your work will directly influence clinical development decisions, regulatory submissions, and payer communications & interactions. By leveraging your expertise in HEOR methodologies, real-world evidence, and cost-effectiveness analysis, you’ll play a pivotal role in enhancing BioNTech’s ability to deliver transformative treatments to diverse populations.
Your contribution:
- Develop and execute Global value evidence generation plans for systematic literature reviews (SLR), indirect treatment comparisons (ITC), cost-effectiveness analyses (CEA), budget impact analyses (BIA), real-world evidence (RWE), and patient-reported outcomes (PRO) to optimize clinical development decisions across all stages of drug development
- Conduct global epidemiology literature reviews to inform multi-regional clinical trial site selection and recruitment strategies
- Provide guidance on FDA regulations related to patient-reported outcomes (PROs) and patient-focused drug development (PFDD), ensuring alignment with labeling claims
- Prepare regulatory-grade documents such as FDA/Global Regulatory briefing books for PRO Endpoint implementation, epidemiology, and pediatric investigation plans
- Lead the implementation of robust evidence synthesis strategies to support global pharmaceutical launches and reimbursement dossiers across HTA markets & Non HTA Markets like PICOS Simulation/Scoping, PICOS feasibility assessment and development JCA dossiers
- Lead the development of early advice (EA) dossiers (Country level and JSC) and actively participate in discussion with relevant stakeholders on the value of the clinical program. Stay at the forefront of industry trends and integrate emerging methodologies into evidence synthesis plans including the use of AI in SLR/ITCs/ RWE and Global Value Evidence tool kit development
- Collaborate with key opinion leaders, including medical experts, through structured engagements like advisory boards and Delphi panels
- Develop pre-approval dossiers, launch models (CEA/BIA), tools, relevant Health Care Economic Information (HCEI) training materials to support US Account Management teams, Medical Science Liaisons, and field-based HEOR professionals
- Support other HEOR team members by reviewing their evidence generation plans, publications and offering constructive- solution oriented feedback.
- Mentor HEOR fellows and early-career team members while providing constructive feedback on evidence generation plans
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A good match:
- MS required; Doctoral degree (PhD/PharmD/MD) preferred in Public Health, Epidemiology, Health Economics, or related fields with significant experience conducting HEOR research
- At least 5 years of relevant experience (or 10 years with MS degree) conducting HEOR research across methodologies such as SLR, ITC/NMA/MAIC/STC, CEA/BIA models, RWE designs, and PRO analytics
- Expertise in US/Ex-US real-world data sources (e.g., Komodo, Optum, Medicare RIF) with proficiency in study design evaluation and improvement
- Experience with eCOA implementation preferred; familiarity with FDA COA Type C meetings and negotiating PRO label claims a plus
- Proven track record of peer-reviewed publications showcasing HEOR expertise across multiple domains
- Deep understanding of EU-HTA requirements including JSC/EA/JCA implementation alongside knowledge of global health technology assessment guidelines
- Excellent communication skills with experience presenting HEOR research to payers/population health decision-makers
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Join BioNTech’s dedicated team to lead transformative health economics research that shapes the future of healthcare globally!
Your benefits and remuneration:
If the position is filled in the US, the Expected Pay Range is $168,100/year to $268,700/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.
Compensation at other locations may vary significantly.
BioNTech is committed to the wellbeing of our team members and offers a variety of benefits in support of our diverse employee base. We offer competitive remuneration packages which is determined by the specific role, location of employment and also the selected candidate’s qualifications and experience.
Note: The availability, eligibility and design of the listed benefits may vary depending on the location. The final requirements for the individual use of our benefits are based on the company's internal policies and applicable law.
How to apply:
Apply now by sending us your application documents including Curriculum Vitae, copy of ID, copies of degree certificates and professional certificates, motivation letter as well as your contact details via our online form.
Please note:
Only applications sent via our online form shall be considered. By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.
We are looking forward to receiving your application.
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