RTI International
Executive Director, Evidence Synthesis & Statistics
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Executive Director, Evidence Synthesis & Statistics (ESS) – RTI Health Solutions
About the Hiring Group
RTI Health Solutions (RTI-HS) is a leading provider of global health economics and outcomes research (HEOR), real-world evidence (RWE), epidemiology, and market access consulting services. Our multidisciplinary teams partner with clients across the product lifecycle to generate evidence that informs regulatory, reimbursement, and commercialisation decisions.
The Evidence Synthesis & Statistics (ESS) capability plays an important role in helping clients evaluate the clinical, humanistic, and economic value of healthcare interventions. The team delivers evidence synthesis, advanced statistical analysis, and strategic evidence planning to support HTA, regulatory, payer, market access, and evolving Joint Clinical Assessment (JCA) decision-making globally.
We are seeking an accomplished scientific leader to lead and grow RTI-HS’s ESS capability. This individual will provide strategic, scientific, and operational leadership for evidence synthesis and statistical services while remaining hands-on in the delivery of complex client work.
What You'll Do
Scientific & Strategic Leadership
- Lead and grow RTI-HS’s Evidence Synthesis & Statistics capability, establishing a market-leading practice focused on evidence generation, advanced analytics, and decision support
- Serve as a senior scientific advisor to pharmaceutical and biotechnology clients on evidence synthesis methodologies and evidence generation strategy
- Provide technical leadership, hands-on methodological input, and quality assurance across a wide range of evidence synthesis activities
- Lead and directly contribute to complex analytical work, including:
- Bayesian methods
- Causal inference
- Patient-reported outcomes (PRO) analysis
- Survival analysis
- Mixed effects/hierarchical modeling
- Network meta-analysis
- Indirect treatment comparisons (ITCs), including:
- Matching-adjusted indirect treatment comparisons (MAICs)
- Simulated treatment comparisons (STCs)
- Advise on integrated evidence strategies aligning clinical development, HEOR, RWE, market access, and publication objectives
- Drive innovation in methods, ensuring adoption of new and evolving approaches and continuous improvement in delivery
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Business Development & Client Leadership
- Lead business development activities, including:
- Identifying opportunities
- Developing proposals
- Supporting client presentations and scientific meetings
- Contributing senior scientific insight throughout the sales process
- Partner with commercial and scientific leaders across RTI-HS to expand the visibility and market position of the ESS capability
- Act as a senior client contact, building long-term relationships and providing strategic and methodological input across engagements
- Monitor industry trends, HTA, payer, and evolving JCA evidence requirements, and competitive landscape to inform service development
Operational & People Leadership
- Build, mentor, coach, and develop a high-performing team of evidence synthesis statisticians
- Oversee project delivery, ensuring:
- Scientific rigour
- Client satisfaction
- Financial performance
- Lead complex projects and portfolios, ensuring alignment to timelines, budgets, quality standards, and client expectations
- Ensure appropriate tools, processes, and methodological standards are in place and continuously improved
- Foster collaboration across HEOR, RWE, Epidemiology, Market Access, and Biostatistics to deliver integrated solutions
Thought Leadership & External Engagement
- Represent RTI-HS through:
- Conference presentations
- Publications
- Workshops
- Webinars
- Build the external scientific profile of the ESS capability through:
- Engagement with the research and HTA community
- Active involvement with Joint Clinical Assessment (JCA)
- Contribute to the advancement of evidence synthesis methodologies, promoting innovative approaches using:
- AI
- Automation
- Advanced analytics
- Emerging technologies (where appropriate)
- Support development of internal best practices, methodological guidance, and reusable intellectual capital
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What You'll Need
-
Advanced degree (PhD, DrPH, ScD, MD, PharmD, or equivalent) in:
- Epidemiology
- Health economics
- Biostatistics
- Public health
- Pharmacy
- Or a related scientific discipline
- Minimum 12+ years of relevant experience
-
Significant relevant experience leading evidence synthesis activities within:
- A pharmaceutical company
- CRO
- Consulting organisation
- Academic research environment
-
Deep expertise in:
- Network meta-analysis
- Other indirect treatment comparison methods
- Advanced statistical methods
- Broader evidence generation strategy
-
Demonstrated success in:
- Leading multidisciplinary project teams
- Managing complex client engagements
-
Proven business development experience, including:
- Proposal leadership
- Client relationship management
- Revenue generation
-
Strong expertise across:
- Advanced statistical and evidence synthesis methodologies:
- Bayesian approaches
- Network meta-analysis
- Other indirect comparisons (e.g., MAIC)
- Survival analysis
- Health utility analysis (e.g., EQ-5D)
- Advanced statistical and evidence synthesis methodologies:
-
Familiarity with:
- Emerging methods (e.g., target trial emulation)
- Evolving evidence synthesis techniques
-
Advanced programming skills in:
- R and/or STATA
-
Strong understanding of:
- Global HTA, payer, and evolving JCA evidence requirements
- Role of evidence synthesis across the product lifecycle
-
Exceptional communication and presentation skills, with the ability to engage:
- Scientific audiences
- Commercial stakeholders
- Executive leadership
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