Medicines and Healthcare products Regulatory Agency
Infrastructure Operations Engineer

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Infrastructure Operations Engineer
We are currently looking for an Infrastructure Operations Engineer to join our Clinical Practice Research Datalink Team in the Safety and Surveillance group.
This is a full-time opportunity, on a permanent basis. The role will be based in 10 South Colonnade, Canary Wharf London. Please be aware that this role can only be worked in the UK and not overseas.
Government departments and agencies are working towards implementing a minimum 60% attendance in office sites.
We are currently implementing a flexible, hybrid way of working, with a minimum of 8 days per month working on site to enable the collaboration and contact with partners and stakeholders needed to deliver MHRA business. Attendance on site is driven by business needs so depending on the nature of the role, this can flex up to 12 days a month, with the remainder of time worked either remotely or in the office. Some roles will need to be on site more regularly. Remote working is potentially available for some specific roles. Please discuss this with the recruiting manager before accepting an appointment.
Who are we?
The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research.
The Safety and Surveillance Group brings together into a single integrated structure devices and medicines safety expertise with enforcement capabilities. These functions will be supported by our data and evidence generating capabilities complementing our signal generating capabilities produced via the new Safety Connect System.
Part of the Safety and Surveillance group, The Clinical Practice Research Datalink (CPRD), with support from the National Institute for Health and Care Research (NIHR), is the UK’s preeminent research service providing access to anonymised NHS data for research. In addition to supporting high quality observational research, CPRD has developed world leading services based on using real world data to support clinical trials and interventional studies.
What’s the role?
The CPRD Infrastructure Operations Engineer role offers an exciting opportunity to support and enhance the UK Government’s premier data-driven health research service. The successful candidate will play a key role in the operation, support and continual improvement of CPRD’s Azure cloud platforms and research services.
Working within the Infrastructure Team, you will be responsible for maintaining secure, resilient and highly available cloud infrastructure that underpins CPRD’s research environments, data platforms and business-critical services. You will work closely with internal stakeholders, technical teams and external suppliers to ensure operational excellence across the estate.
The role requires a proactive individual who can take ownership of operational activities, investigate and resolve technical issues, support infrastructure changes and contribute to service improvements. You will have opportunities to develop your Azure expertise, contribute to strategic initiatives and support innovative research platforms used by healthcare researchers across the UK.
Key responsibilities:
- Maintain the effective operation of CPRD’s research IT systems.
- Develop and implement IT Service improvements.
- Manage incidents and resolve problems.
- Liaise with service providers and partners.
Who are we looking for?
Our successful candidate will have the following:
- Educated to degree level, or equivalent, in either a computer science-based, IT-based, or related discipline or industry qualifications at a professional level such as ITIL Foundation.
- Have hands-on experience in maintaining Azure service components to ensure they meet business needs and performance targets.
- Have awareness in carrying out the routine configuration, installation, and reconfiguration of IT systems, optimizing performance, scripting, and forecasting resource needs.
- Have awareness of investigating problems in systems, processes, and services, determining the appropriate remedy, and assisting with the implementation of remedies and preventative measures.
- Have awareness of implementing changes based on requests for change and applying change control procedures.
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Person Specification:
Method of assessment: A=Application, I=Interview, T=Test, P=Presentation
Behaviour Criteria:
- Managing a Quality Service (A/I)
- Delivering at Pace (A/I)
- Making Effective Decisions (A/I)
- Working Together (A/I)
Experience Criteria:
- Proven experience managing IT infrastructure in an Azure cloud environment. Strong understanding of Azure services, including computing, storage, networking, and identity management. (A/I/T)
- Hands-on experience with Azure DevOps, automation tools (e.g., PowerShell, Azure CLI), and configuration management. (A/I)
- Familiarity with Active Directory and role-based access control (RBAC).
- Working knowledge of cybersecurity best practices and compliance standards in cloud environments. (A/I)
- Prior responsibility for using business information management systems to effectively monitor, track, and report data usage against agreed metrics and targets. (A/I)
- Knowledge of using project management techniques to deliver required outcomes, identify risks, and implement mitigating actions. (A/I)
Technical Criteria:
- Educated to undergraduate degree level in either a maths, information technology, or computer science-based subject or equivalent work-related experience. (A)
- Certifications such as Microsoft Certified: Azure Administrator Associate or Azure Solutions Architect Expert. (A/I)
If you would like to find out more about this fantastic opportunity, please read our Job Description and Person Specification! [https://mhra-gov.filecamp.com/s/d/j3kpLEEvSKoHjuUS]
Please note: The job description may not open in some internet browsers. Please use Chrome or Microsoft Edge. If you have any issue viewing the job description, please contact careers@mhra.gov.uk
The selection process:
We use the Civil Service Success Profiles to assess our candidates, find out more here [https://www.gov.uk/government/publications/success-profiles].
- Online application form, including questions based on the Behaviour, Experience and Technical Success Profiles. Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application.
- Test, further information will be supplied when you reach this stage
- Interview, which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles.
In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of: Proven experience managing IT infrastructure in an Azure cloud environment. Strong understanding of Azure services, including computing, storage, networking, and identity management.
Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the competency-based answers provided- ensure you have read these thoroughly and allow sufficient time. You can view the competencies for this role in the job description.


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Use of AI in Job Applications
Artificial Intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance [https://www.civil-service-careers.gov.uk/artificial-intelligence-and-recruitment/] for more information on appropriate and inappropriate use.
If you require any disability related adjustments at any point during the process, please contact careers@mhra.gov.uk as soon as possible.
Closing date: Monday 17th August 2026
Shortlisting date: Friday 21st August 2026
Interview date: Thursday 3rd September 2026
Candidates will be contacted within a week of the sift and the interviews completed to inform them of the outcome.
If you need assistance applying for this role or have any other questions, please contact careers@mhra.gov.uk
Candidates will be subject to UK immigration requirements as well as Civil Service nationality rules. Further information on whether you are able to apply is available here [https://www.gov.uk/government/publications/nationality-rules].
Successful candidates must pass a disclosure and barring security check as well as animal rights and pro-life activism checks. People working with government assets must complete basic personnel security standard checks [https://www.gov.uk/government/publications/government-baseline-personnel-security-standard].
Certain roles within the MHRA will require post holders to have vaccinations, and in some circumstances, routine health surveillance. These roles include:
- Laboratory-based roles working directly with known pathogens
- Maintenance roles, particularly those required to work in laboratory settings
- Roles that involve visiting other establishments where vaccination is required
- Roles required to travel overseas where specific vaccination may be required.
Applicants who are successful at interview will be, as part of pre-employment screening subject to a check on the Internal Fraud Database (IFD). This check will provide information about employees who have been dismissed for fraud or dishonesty offences. This check also applies to employees who resign or otherwise leave before being dismissed for fraud or dishonesty had their employment continued. Any applicant’s details held on the IFD will be refused employment. A candidate is not eligible to apply for a role within the Civil Service if the application is made within a 5 year period following a dismissal for carrying out internal fraud against government.
Any move to the MHRA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility here [https://www.childcarechoices.gov.uk/].
Individuals appointed on level transfer will retain their existing salary and are responsible for ensuring they fully understand the
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