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Normal Development Of The Human Fetus And How Maternal Lifestyle And Environment Influence It Between 7 And 20 Weeks Of Gestation
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Age: 16 Years +
All Genders
Healthy Volunteers
ID: 04613583
Normal Development of the Human Fetus and How Maternal Lifestyle and Environment Influence It Between 7 and 20 Weeks of Gestation
Led by University of Aberdeen
Updated on: 2026-05-05
1200 Participants Needed
1 Research Site
Total Duration
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- AI-Summary
- Brief Title
- Who Can Participate
- AI-Screening
- Your Study Journey
- Trial Site Locations
- Research Team
- How is the study designed?
- Similar Trials
- Frequently Asked Questions
- Research Publications
- Sponsors
AI-Summary
What This Trial Is About
Researchers are examining how various maternal lifestyle and environmental factors such as smoking, alcohol use, drug abuse, prescription medicines, and exposure to chemicals can affect human fetal development. The study focuses on fetuses between 7 and 20 weeks of gestation, a critical period for development, to better understand the mechanisms by which these exposures may cause long-term health issues like obesity, hypertension, metabolic syndrome, and infertility. This observational study aims to provide fundamental knowledge about normal fetal development and how adverse maternal influences can alter it, ultimately affecting health in adulthood. The study involves collecting multiple fetal organs and body fluids from normal pregnancies as well as pregnancies where the mother experiences challenges such as smoking, obesity, or exposure to pollutants. Researchers will use various laboratory and microscopic techniques to analyze hormones, genes, proteins, chemicals, and DNA from fetal tissues. The investigation covers many systems including the endocrine, reproductive, nervous, metabolic, cardiovascular, immune, musculoskeletal, and placental development. There is also a focus on maternal emotional health and its impact on the fetus, as well as a study on nerve repair potential. No active intervention is performed this is a detailed observational research program. Participants will be involved during early pregnancy, with fetal tissue collection occurring between 7 and 20 weeks of gestation. Researchers will gather extensive data on fetal development and maternal lifestyle, including questionnaires related to alcohol use and emotional wellbeing. The main outcome is the creation of a large dataset describing normal fetal development and the effects of maternal environment, which will be used for future research to improve health outcomes. The study includes long-term follow-up of up to 10 years to assess how early fetal exposures relate to adult health and disease risks.
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CONDITIONS
Brief Title
Scottish Advanced Fetal Research Study
Who Can Participate
Age: 16 Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Women at 7-20 weeks of gestation
- Women aged 16 years and older, capable of making a rational decision
- Absence of fetal anomaly at ultrasound scan
- Women who are fluent English speakers
You will not qualify if you...
- Women exhibiting considerable emotional distress
- Fetal anomalies identified at ultrasound scan
Research Team
P
Paul A Fowler, PhD
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On this page
- AI-Summary
- Brief Title
- Who Can Participate
- AI-Screening
- Your Study Journey
- Trial Site Locations
- Research Team
- How is the study designed?
- Similar Trials
- Frequently Asked Questions
- Research Publications
- Sponsors
Sponsors
U
University of Aberdeen
Lead Sponsor
N
NHS Grampian
Collaborating Sponsor
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