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Observational Registry To Determine Predictors And Outcomes Of Patients At Risk Of And Diagnosed With Left Ventricular Thrombus
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Actively Recruiting
Age: 18 Years +
All Genders
Healthy Volunteers
ID: 06963567
Observational Registry to Determine Predictors and Outcomes of Patients at Risk of and Diagnosed With Left Ventricular Thrombus
Led by Queen Mary University of London
Updated on 2026-05-06
1500 Participants Needed
1 Research Site
N/A
Total Duration
On this page
- AI-Summary
- Brief Title
- Who Can Participate
- AI-Screening
- Your Study Journey
- Trial Site Locations
- How is the study designed?
- Similar Trials
- Frequently Asked Questions
AI-Summary
What This Trial Is About
This research aims to better understand left ventricular thrombus (LVT), a blood clot that can form in a weakened heart, especially in people who have had a heart attack or heart failure. About one in six such patients develop these clots, which can lead to serious problems like stroke. The study hopes to gather information on factors linked to clot formation and management to improve care for patients with this condition.
Patients included either have a diagnosed LVT with left ventricular dysfunction related to conditions like acute myocardial infarction or cardiomyopathy, or are at risk due to severe heart dysfunction or heart muscle damage. This is an observational study where no treatments are given instead, participants have routine MRI scans, blood tests, and questionnaires to collect data over time. Participants will provide blood samples at the start and around six months into the study. They will also complete quality of life questionnaires at the beginning and after 12 months. Researchers will record scan results and blood test data and may take additional MRI images during routine scans. The main outcome measured is a composite result assessed from the start to 12 months, with other measures including MRI predictions, blood tests, and quality of life evaluations.
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CONDITIONS
Brief Title
Left Ventricular Thrombus Registry
Who Can Participate
Age: 18 Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Patients with left ventricular thrombus
- Patients at risk for developing left ventricular thrombus, such as those with severe left ventricular dysfunction, left ventricular aneurysm, or myocardial infarction
- Age 18 years or older
- Able to give informed consent
You will not qualify if you...
- Age under 18 years
- Unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
- First name *
- Last name *
- Email Address *
- Phone Number *
- Country Code: +1
- Gender *
- ZIP Code *
- I agree to receive SMS messages from DecenTrialz regarding trial matching, appointment updates, participant updates, and related information. Message frequency varies. Message & data rates may apply. Reply STOP to cancel or HELP for assistance. I also agree to the Terms of Service and Privacy Policy.
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Baseline
Participants undergo baseline assessments including imaging and blood tests to evaluate left ventricular thrombus status and risk factors.
1 visit (in-person)
Long-term Monitoring
Duration - Up to 12 months (+/- 2 months)
Participants are monitored over time to observe outcomes related to left ventricular thrombus and overall health status.
Follow-up visits at 6 months and 12 months
Trial Site Locations
Total: 1 location
- St Bartholomew's Hospital
- London, United Kingdom, EC1A 7BE
Actively Recruiting
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
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On this page
- AI-Summary
- Brief Title
- Who Can Participate
- AI-Screening
- Your Study Journey
- Trial Site Locations
- How is the study designed?
- Similar Trials
- Frequently Asked Questions
Sponsors
Queen Mary University of London
Lead Sponsor
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