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University of Exeter

Postdoctoral Research Associate

Exeter
£34.6k/yr
Posted about 21 hours ago
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Careers Site Advertising End Date

Advertising End Date:

27 Aug 2026

Internal Advertising End Date

Internal Advertising End Date:

Not Specified

All Locations

All Locations:

Exeter

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All Departments

All Departments:

Not Specified

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Type of Contract

Type of Contract:

Fixed-term contract

Advertising Salary

Salary Details:

The starting salary will be from £34,610 on Grade E, depending on knowledge, skills and experience.

About The Role

Postdoctoral Research Associate

INTERNAL APPLICANTS ONLY

This post is offered as a fixed term contract and is funded by Medical Research Council from 1st October 2026 till 30th September 2027. In line with the University’s fair employment for all principles, any further funding opportunities identified will be reviewed and discussed during the contract.

The starting salary will be from £34,610 on Grade E, depending on knowledge, skills and experience.

The Role

The Faculty of Health and Life Sciences wishes to recruit a Postdoctoral Research Associate to support the work of Dr Johannes G. M. Rack. The successful applicant will assist in the characterisation of enzymes involved in ADP-ribosylation signalling in the DNA damage response of Aspergillus fumigatus.

The post will include large scale protein purification for protein crystallisation and their characterisation with respect to activity (enzymatic assays, mutagenesis, inhibitor tests, etc.) and biophysical properties (incl. determination of binding and kinetic parameters). Knowledge of ADP-ribosylation related enzymes and how they can be expressed and characterised is essential. Moreover, the project involves extraction and characterisation of proteins from Aspergillus fumigatus (IP/Co-IP) and requires expertise in Aspergillus fumigatus culture and maintenance. Knowledge of proteomic and IP techniques is advantageous.

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About You

The successful applicant will be able to present information on research progress and outcomes, communicate complex information, orally, in writing and electronically and prepare proposals and applications to external bodies.

Applicants will possess a relevant PhD (or nearing completion) or possess an equivalent qualification/experience in a related field of study and be able to demonstrate sufficient knowledge in the discipline and of research methods and techniques to work within established research programmes. Applicants will be able to demonstrate practical experience with the characterisation of ADP-ribosylation signalling related enzymes including protein expression and structure determination, application of biochemical and biophysical methodologies as well as a understanding of fungal DNA damage response and the role of ADP-ribosylation signalling therein.

Please ensure you read the Job Description and Person Specification for full details of this role.

Further information

Please contact Johannes Rack, j.rack@exeter.ac.uk

About The Division

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About Us

Transform Your Career and Help Shape a Greener, Healthier, and Fairer Future

Join the University of Exeter, a top 200 Russel Group university (QS & THE World University Rankings 2025), excelling in teaching (triple Gold rating, TEF 2023) and leading groundbreaking research in the beautiful southwest of England.

We are committed to understanding different cultures and perspectives, supporting diverse leadership, and striving for social justice. We encourage applications from all groups underrepresented in our community, including racially minoritised individuals and those with disabilities. Our inclusive, merit based recruitment processes seek to embrace a diverse set of experiences to ensure colleagues feel supported equitably. With over 30,000 students and 7,000 staff from 140 countries, we foster a culture where everyone can thrive.

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You can read more about our current accreditations and commitment to Equality, Diversity and Inclusion here, including our commitment to the Armed Forces Covenant.

What We Can Offer You

  • Freedom (and the support) to pursue your intellectual interests and to work creatively across disciplines;
  • Support teams that understand the University wide teaching goals and partner with our academics accordingly;
  • An Innovation, Impact and Business directorate that works closely with our academics providing specialist support for external engagement and development;
  • Our Exeter Academic initiative supports high performing academics to achieve their potential and develop their career;
  • A multitude of staff benefits including sector leading benefits around maternity, adoption and shared parental leave (up to 26 weeks full pay), paternity leave (up to 6 weeks full pay), and a Fertility Treatment Policy;
  • A beautiful campus set in the heart of stunning Devon/Cornwall.

How We Can Help

If you are considering applying and need support to do so, please get in touch with us at hrhelpdesk@exeter.ac.uk. You can request reasonable adjustments within your application or by contacting us. You can also choose to be considered under our Disability Confident Scheme and find out here how this is managed during our recruitment and onboarding process.

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Skills

Protein Purification
Protein Crystallisation
Enzymatic Assays
Mutagenesis
Biophysical Characterisation
Aspergillus Fumigatus Culture
Immunoprecipitation
Co-Immunoprecipitation
Proteomics
ADP-ribosylation Signalling
DNA Damage Response
Scientific Writing
Grant Proposal Preparation

Location

Exeter, England, United Kingdom

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