Earlham Institute
Postdoctoral Research Scientist - Bioinformatics

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Protist Omics at Scale - Computational Biologist
The Earlham Institute has been awarded funding by the Gordon and Betty Moore Foundation to develop Protist Omics at Scale, a three-year international methods-development programme run in partnership with the Scottish Association for Marine Science, home of the Culture Collection of Algae and Protozoa, and Aalborg University.
We are looking for a computational biologist to lead the computational core of the project: quality control, assembly, decontamination and co-biont separation, and structural and functional annotation across all three aims. Where existing tools fail, the postholder will diagnose why and develop what replaces them.
This is a postdoctoral computational biology/bioinformatics role focused on developing and applying novel methods for long-read and single-cell genome and transcriptome assembly across a diverse range of protist species.
Responsibilities
The postholder will:
- Develop expertise in advanced genome and transcriptome assembly approaches.
- Work on complex long-read and single-cell sequencing datasets.
- Contribute to the development of new computational methods rather than routine analysis.
- Develop research software engineering skills, including workflow development, packaging, and containerisation.
- Create and maintain reproducible bioinformatics workflows using platforms such as Galaxy and WorkflowHub.
- Collaborate closely with internal and external partners across the consortium.
- Lead or contribute significantly to project outputs.
- Publish research findings and present at national and international conferences.
- Participate in workshops, hackathons, and community training activities.
- Support the supervision and development of students where appropriate.
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Career Opportunities
The role offers extensive opportunities for career development, networking, and collaboration within an internationally recognised genomics research environment.
Candidate Profile
The ideal candidate:
- Will have, or be close to completing, a PhD in bioinformatics, computational biology, genomics, evolutionary biology, or a closely related discipline.
- Will have practical experience of analysing large-scale next-generation sequencing datasets and de novo genome assembly using long-read sequencing data (PacBio HiFi and/or Oxford Nanopore), together with proficiency in at least one bioinformatics programming language and experience working in a Linux/HPC environment.
- Will have experience of genome or transcriptome analysis, an ability to critically evaluate computational methods, and a track record of contributing to research outputs, including peer-reviewed publications.
- Experience of workflow development and reproducible research practices, including version control and workflow management systems, would be advantageous, as would knowledge of single-cell genomics, protist or microbial eukaryote biology, and software containerisation technologies.


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Job Details
- This is a full-time post for a contract of 36 months.
- This role meets the criteria for a visa application, and we encourage all qualified candidates to apply.
- As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
- The closing date for applications will be 1 October 2026.
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