Nexus Life Sciences
Principal Scientist

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🧪 Principal Scientist – Analytical
🚀 Location: Sandwich
đź’° Salary: Up to ÂŁ57,000 per annum
Job Type: Permanent | Full-time (37.5 hours)
A leading UK scientific organisation is seeking an experienced Principal Scientist (Analytical) to provide senior scientific leadership and hands-on expertise across a diverse portfolio of client projects. This is a high-impact role for an analytical specialist who excels at method development, problem-solving, and driving high-quality data delivery within regulated environments.
The Role
You will shape analytical strategy, design and interpret complex studies, and act as a trusted scientific partner to multidisciplinary teams. Combining technical authority with practical laboratory work, you’ll ensure analytical approaches are robust, compliant, and aligned with project and regulatory expectations.
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Alongside project delivery, you’ll play a key role in mentoring colleagues, strengthening analytical capability, and fostering a collaborative, high-performing scientific culture.
Key Responsibilities
- Lead analytical strategy and delivery across small molecules and emerging modalities.
- Design, execute, and interpret complex analytical studies to support process development and technical investigations.
- Provide expertise across techniques such as UPLC-MS, SFC, NMR, GC-MS, and advanced characterisation methods.
- Drive method development, validation, troubleshooting, and continuous improvement.
- Collaborate with R&D chemists, process chemists, project teams, quality colleagues, and clients.
- Uphold the highest standards of data integrity, safety, and regulatory compliance.
- Mentor and develop scientists, supporting capability building and knowledge sharing.
- Manage projects effectively, ensuring timelines, quality, and client expectations are met.


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About You
You will bring:
- A PhD in Chemistry (or equivalent postgraduate qualification).
- Strong experience in method development / analytical development.
- A solid background in drug substance / API analytical science.
- Proven experience managing projects within a scientific or regulated environment.
- Broad technical expertise across modern analytical instrumentation.
- A passion for delivering high-quality, compliant analytical science.
- A collaborative, supportive approach to mentoring and team development.
- Ideally, experience working within GMP-regulated analytical laboratories.
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