Rodeo
Get started

BiVictriX Therapeutics Ltd

Principal Scientist / Head of R&D (Immunology / Immuno-Oncology)

Manchester
£50k – £60k/yr
Posted about 22 hours ago
Sign up to applySee more jobs like this
Get notified of more jobs like this · No spam, ever

How your CV stacks up

1Upload CV
2Analyse CV
3Improve CV

Upload your CV to see how well it fits this job role

?%

About BiVictriX

BiVictriX is a preclinical-stage biotechnology company developing the next generation of highly selective cancer therapeutics using its proprietary Bi-Cygni® technology platform.

Unlike conventional targeted therapies that rely on a single tumour-associated antigen, BiVictriX identifies unique cell-surface co-expression signatures that enable diseased cells to be distinguished from healthy cells at the single-cell level. This approach is designed to overcome one of the greatest challenges in oncology: the lack of tumour-specific targets, by enabling highly selective targeting of malignant cells while minimising damage to healthy tissues.

Leveraging this platform, BiVictriX is advancing a pipeline of first-in-class bispecific Antibody Drug Conjugates (ADCs) designed to deliver enhanced precision, broaden efficacy across heterogeneous tumours and improve therapeutic durability.

The Opportunity

We are seeking an experienced and highly motivated individual with expertise in tumour immunology and translational oncology to join our team.

Reporting directly to the CEO/CSO, the successful candidate will play a key scientific leadership role in shaping and executing the biological strategy across BiVictriX’s ADC portfolio. The role will encompass the design, oversight and interpretation of internal and external discovery, translational and preclinical studies, with a particular focus on understanding the biological mechanisms underpinning therapeutic efficacy and differentiation through tumour microenvironment (TME) engagement.

This is an excellent opportunity for an accomplished scientist who enjoys working in a fast-paced biotech environment and wishes to contribute directly to the advancement of first-in-class therapeutics.

Key responsibilities

  • Provide scientific leadership across biological aspects of BiVictriX’s therapeutic programmes, ensuring delivery of high-quality, decision-enabling data.
  • Design, oversee and interpret in vitro, ex vivo and in vivo studies to evaluate the biological activity, mechanism of action and translational potential of BiVictriX’s ADC candidates, with a strong focus on evaluating therapeutic activity against key cell types within the TME.
  • Lead the scientific management of external CROs, academic collaborations and strategic partners, including study design, execution, budget management, timelines and data review.
  • Develop and implement innovative translational strategies to support target validation, biomarker development, patient selection and indication prioritisation.
  • Guide the development of biologically relevant assays and experimental models to interrogate tumour biology, immune cell interactions and therapeutic response.
  • Maintain a deep understanding of the competitive landscape across relevant tumour indications and therapeutic modalities, incorporating external insights into programme strategy.
  • Support cross-functional project leadership across biology, protein sciences and bioconjugation activities to ensure alignment with development objectives and timelines.
  • Conduct selected laboratory-based studies and provide technical mentorship to members of the biology team where required.
  • Present scientific data internally, to collaborators, at scientific conferences and to potential investors or strategic partners.
  • Contribute to scientific publications, intellectual property generation and broader company strategy.

Reasons to use Rodeo

I’m in my final year doing Economics and I don’t know whether to apply for grad schemes now or do a masters first. What do you think?

Honest answer — it depends on where you want to end up. A lot of top grad schemes (Big 4, civil service, banking) don’t need a masters. Let’s look at the ones you’d be competitive for now, and we can decide if a masters actually adds anything.

Also worth knowing: most autumn 2026 applications are open now. Timing matters more than you think.

Start with a chat, not a search bar

Grad scheme, placement, apprenticeship? Not sure what you want yet — that's fine. Your agent talks it through with you and turns "I have no idea" into a shortlist.

P

Graduate Consultant — 2026 Scheme

PwC·London, UK
£35,000/yr

Why you're a good match

Strong

Your economics background and your summer at a regional bank line up with what PwC looks for on the consulting scheme. Applications close in four weeks.

See breakdown
Save jobNot relevant
View details

It searches the market for you

Every day your agent scans the market matching roles against what actually matters to you, not just keywords on a CV.

Why you're a good match

You’ve got the grades and the economics background, and your bank internship is exactly the experience this scheme looks for. Apply soon — deadlines close within the month.

See breakdown
Strong

Experience fit

Your summer at the bank plus your econometrics coursework map directly to the day-one responsibilities on this scheme — client modelling, market briefings, and deal support.

See breakdown
Strong

Only hits

No noise. No "maybe this fits." Just roles with a clear explanation of why they're right — and where to focus when applying.

Essential Qualifications and experience

  • PhD in Immunology, Cancer Biology, or a related life sciences discipline with a minimum of 5 years’ relevant biotechnology or pharmaceutical industry experience; or MSc with substantial equivalent industry experience.
  • Strong expertise in tumour immunology and/or evaluating key myeloid populations within inflammatory and immune-related diseases (including fibrosis).
  • Significant experience working with components of the tumour microenvironment, including tumour-associated macrophages (TAMs), cancer-associated fibroblasts (CAFs), myeloid-derived suppressor cells (MDSCs) and/or related pathological immune populations within immunology and inflammatory diseases.
  • Demonstrated experience designing and interpreting preclinical oncology/fibrosis studies, including in vivo efficacy models and translational investigations.
  • Proven experience managing external CROs, academic collaborators and research programmes.
  • Strong publication record and ability to communicate complex scientific concepts effectively to diverse audiences.
  • Excellent project management, organisational and communication skills.
  • Ability to thrive in a dynamic, entrepreneurial biotechnology environment and operate effectively across multiple projects.

Get help with your application

Your very own career expert that helps elevate your application to the next level.

Get help applying for this job

Desirable Experience

  • Experience supporting the development of biologics, antibody therapeutics or antibody-drug conjugates.
  • Previous involvement in translational biomarker strategy and patient stratification approaches.
  • Experience in histopathology, immunohistochemistry (IHC), immunofluorescence (IF) and spatial biology techniques.
  • Previous line management, mentoring or scientific leadership responsibilities.
  • Experience contributing to regulatory documentation, investor materials or business development activities.

What we offer

  • Opportunity to contribute directly to the development of first-in-class oncology therapeutics.
  • Exposure to scientific, strategic and operational aspects of an innovative biotechnology company.
  • A collaborative, entrepreneurial and scientifically ambitious working environment.
  • The opportunity to work alongside a highly experienced team developing differentiated ADC technologies.

Start Date

ASAP

Benefits

  • Salary: £50k - £60k / negotiable, depending on experience
  • 25 days annual leave plus Bank Holidays
  • Company pension scheme – access to salary sacrifice subject to eligibility and scheme terms
  • Pleasant office and laboratory environment on rural business park, close to Manchester
  • Free, on-site parking

To apply

Please email your CV and cover letter to careers@bivictrix.com

Important: Your cover letter must confirm in the first paragraph:

  • Your UK right to work status
  • Relevant qualifications and experience
  • Salary expectations with justification
Trusted by 25,000+ job seekers

“It took my CV and asked me questions relevant to understanding what kind of jobs to suggest for me. Suggestions were almost perfect. Jobs were exactly what I’ve been looking for.”

Jessica, London

Get help applying for this job

Location

Manchester, England, United Kingdom

Sign up to applySee more jobs like this