About You

You will be an accomplished PK/PD modelling scientist with substantial experience supporting pharmaceutical drug discovery and/or development programmes.

You will bring:

• A BSc or higher degree in a relevant quantitative or scientific discipline, such as mathematics, engineering, bioscience or pharmaceutical sciences.
• Significant industry experience delivering PK/PD modelling and simulation programmes.
• In-depth knowledge of PK/PD modelling principles and methodologies, including:
  • Compartmental PK
  • Exposure-response modelling
  • Direct and indirect response models
  • Mechanistic and semi-mechanistic PK/PD
  • Disease progression modelling
  • Population modelling approaches
• Experience using relevant modelling and analytical software, such as MATLAB, NONMEM, Monolix, Phoenix WinNonlin, R, or equivalent platforms.
• Broad knowledge of PK, DMPK, quantitative pharmacology and translational science across drug discovery and development.
• Strong understanding of the biological and pharmacological drivers of drug response, including target engagement, biomarkers, efficacy, safety and sources of variability.
• Experience translating modelling outputs into practical recommendations relating to compound progression, dose and regimen selection, study design and risk mitigation.
• Strong quantitative skills encompassing model development, parameter estimation, model qualification, simulation, sensitivity and uncertainty assessment, and the interpretation of complex datasets.
• Experience working within multidisciplinary and matrix project teams.
• A track record of scientific leadership, stakeholder engagement and influencing project decisions.
• Evidence of scientific publications and presentations.
• Excellent written and verbal communication skills, with the ability to explain complex quantitative findings clearly to scientific and non-specialist audiences.

Desirable Experience

It would be advantageous if you also have:

• A PhD in a relevant quantitative or scientific discipline.
• Experience working across global teams, cultures and organisational boundaries.
• Knowledge of both small molecules and larger or novel modalities, including monoclonal antibodies, antibody-drug conjugates and peptides.
• Experience integrating PK, pharmacology, biomarker, efficacy and safety data to inform translational and clinical decisions.
• Experience applying quantitative pharmacology analyses to regulatory submissions or interactions with regulatory authorities.

What You’ll Bring To The Team

Beyond your scientific expertise, you will be:

• Passionate about scientific innovation and solving complex drug-development challenges.
• Comfortable operating both independently and collaboratively.
• Able to adapt your communication and working style to different clients, cultures and project environments.
• An effective mentor who enjoys developing scientific capability in others.
• Confident influencing senior stakeholders and multidisciplinary project teams.
• Commercially aware, with an understanding of how scientific excellence supports client relationships and business growth.

Why Join Us?

This role offers the opportunity to:

• Shape the future direction of PK/PD modelling and quantitative pharmacology within a global drug discovery and development organisation.
• Influence programmes from early discovery through clinical development.
• Work on scientifically diverse client projects across therapeutic areas and molecular modalities.
• Collaborate with multidisciplinary scientific teams around the world.
• Develop people, modelling capability and innovative quantitative services.
• Build your external scientific profile through publications, conferences and industry engagement.

If you are an established PK/PD modelling scientist ready to combine technical leadership, client engagement and strategic capability development, we would be pleased to hear from you.

Apply now to help translate complex data into better drug-development decisions.

Collaborative Culture

Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.