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Physiomics plc

Quantitative Pharmacology Lead / Lead Pharmacometrician

United Kingdom
Posted about 23 hours ago
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Remote UK/EU | Permanent

Physiomics is a quantitative pharmacology and Biometrics consultancy supporting biotech and pharma clients across drug development. We are looking for an experienced pharmacometrician for a hands-on senior role combining technical delivery, client leadership, business development and scientific strategy.

What you'll do:

  • Develop and apply population PK, PK/PD, exposure-response and clinical trial simulation models using R or comparable tools
  • Work hands-on with preclinical and clinical data, from data preparation through model development, diagnostics, simulation, interpretation and reporting
  • Lead client projects from scientific question and modelling strategy through to delivery and actionable recommendations
  • Apply or oversee other approaches including NCA, QSP/mechanistic modelling and PBPK
  • Develop analysis plans, reproducible code and technical reports
  • Work with Business Development to define client solutions, scope work and contribute to pricing, proposals and pitches
  • Build client relationships, identify follow-on opportunities and support new service development
  • Stay current with pharmacometrics, MIDD, regulatory guidance and emerging methods, and represent Physiomics at conferences and industry events

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I’m in my final year doing Economics and I don’t know whether to apply for grad schemes now or do a masters first. What do you think?

Honest answer — it depends on where you want to end up. A lot of top grad schemes (Big 4, civil service, banking) don’t need a masters. Let’s look at the ones you’d be competitive for now, and we can decide if a masters actually adds anything.

Also worth knowing: most autumn 2026 applications are open now. Timing matters more than you think.

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Graduate Consultant — 2026 Scheme

PwC·London, UK
£35,000/yr

Why you're a good match

Strong

Your economics background and your summer at a regional bank line up with what PwC looks for on the consulting scheme. Applications close in four weeks.

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Why you're a good match

You’ve got the grades and the economics background, and your bank internship is exactly the experience this scheme looks for. Apply soon — deadlines close within the month.

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Strong

Experience fit

Your summer at the bank plus your econometrics coursework map directly to the day-one responsibilities on this scheme — client modelling, market briefings, and deal support.

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What you'll bring:

  • Typically 8+ years in pharma, biotech, CRO or consultancy, with recent hands-on modelling responsibility
  • Deep expertise in population PK, PK/PD, exposure-response modelling and clinical trial simulation
  • Strong practical capability in R and NONMEM or comparable tools
  • Experience leading complex modelling projects and working directly with clients or cross-functional development teams
  • Strong understanding of regulatory expectations for pharmacometrics and MIDD
  • PhD or equivalent advanced qualification in a relevant quantitative discipline

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Preferred

  • Direct experience in Clinical Development including regulatory interactions
  • Consultancy solutioning, pricing, proposals or business development
  • Experience leading or line-managing small scientific or technical teams

Why Physiomics?

Work across multiple clients, assets and development stages while staying close to the science, with direct client exposure and the opportunity to shape new capabilities.

Apply via this LinkedIn job advert or send your CV to info@physiomics.co.uk.

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Skills

Population PK
PK/PD Modelling
Exposure-Response Modelling
Clinical Trial Simulation
R
NONMEM
NCA
QSP
PBPK
MIDD
Business Development
Client Leadership
Scientific Strategy
Regulatory Guidance
Data Preparation
Technical Reporting

Location

United Kingdom

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