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University of Cambridge

Research Assistant (Fixed Term)

Cambridge
Posted 1 day ago
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Job Description

We seek to recruit a highly enthusiastic and motivated full-time Research Assistant to work on a British Heart Foundation-funded translational project in the Wilson group in the Department of Pharmacology (https://www.phar.cam.ac.uk/research/Wilson), based at the Gurdon Institute.

About the Role

The goal of this project is to optimise a novel, transformative cardiac regenerative therapeutic.

After a heart attack, there is an irreversible loss of cardiac tissue with ensuing heart failure. The Wilson group has pioneered the use of a novel RNA therapeutic to coax cardiomyocyte proliferation and recover cardiac function in the infarcted heart. Our strong in vitro and in vivo studies indicate a realistic potential to repair and remuscularise a damaged adult heart. This project will design and test mRNA sequence structures to enable optimal therapeutic outcomes and pioneer a transformative cardiac regeneration therapy to eventually eradicate heart failure and its complications.

Responsibilities

  • Work in the Wilson group in the Gurdon Institute, Cambridge University
  • Develop and test novel RNA-based therapeutics in vitro and in vivo
  • Manage research activities and generate high-quality data
  • Present data and update the project team monthly
  • Work collaboratively with external partners
  • Take a lead in your area of research and contribute intellectually to the direction of the research project

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Requirements

  • Experienced in cardiovascular research
  • Experience in molecular and cellular biological techniques, including bacterial cloning, mRNA synthesis, tissue culture, including ES cells and differentiation, histological expertise, and microscopic image analysis
  • Experience in, or a willingness to learn, in vivo biology is essential
  • Holding a Home Office Personal Licence is desirable
  • Candidates should hold or be close to completing minimally an MSc degree in an appropriate field or have relevant experience at an equivalent level, ideally with proven hands-on lab experience
  • Candidates should be highly motivated and productive with an enthusiastic approach to science
  • Exceptional organisational skills
  • Skilled at presenting data, verbally and in writing
  • Committed to collaborative and interdisciplinary research and able to work both independently and as part of a research team

Application

Applications are particularly welcome from women, black and minority ethnic candidates.

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Please ensure that you upload your Curriculum Vitae (CV) including a publication list and a covering letter in the Upload section of the online portal. Please also include names and contact details (e-mail and phone number) of two referees. Any other unsolicited documents will not be considered. Please submit your application by midnight on the closing date.

Additional Information

  • Fixed-term: The funds for this post are available for 18 months based upon successful accomplishment of milestones
  • The University actively supports equality, diversity, and inclusion and encourages applications from all sections of society
  • The University has a responsibility to ensure that all employees are eligible to live and work in the UK

Application Process

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Contact Information

Informal enquiries are welcomed and should be directed to Dr Catherine Wilson, chw39@cam.ac.uk

For enquiries about the online application process please contact the HR Team, HR@phar.cam.ac.uk

Please quote reference PL50479 on your application and in any correspondence about this vacancy.

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Skills

Cardiovascular Research
Molecular Biology
Cellular Biology
Bacterial Cloning
mRNA Synthesis
Tissue Culture
ES Cells Differentiation
Histological Expertise
Microscopic Image Analysis
In Vivo Biology
Data Presentation
Collaborative Research

Location

Cambridge, England, United Kingdom

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