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University of Cambridge

Research Assistant in the Vitreoretinal Research Group

Cambridge
Posted about 19 hours ago
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Applications are invited for a full-time Research Assistant to join the Vitreoretinal Research Group in the Department of Clinical Neurosciences

The post will support a project using single-cell transcriptomics to characterise cells in human vitreous and surgically excised vitreoretinal membranes, improving understanding of retinal detachment and related disease.

The successful applicant will undertake the core laboratory work: processing fresh ocular samples; optimising tissue dissociation, cell recovery and viability; preparing high-quality single-cell suspensions; and undertaking or supporting single-cell RNA-sequencing library preparation and quality control. They will work with bioinformatics colleagues, help interpret analytical outputs, and contribute to figures, reports and publications. The role may include associated cell-culture or molecular-biology experiments.

Applicants should have:

  • A degree in biological sciences, biomedical sciences or a related discipline, with practical experience in molecular biology or genomics.
  • Experience of next-generation sequencing library preparation and quality control.
  • The ability to interpret experimental and sequencing results and communicate them clearly.
  • Familiarity with R or similar analytical software, single-cell or low-input sequencing workflows, primary human tissue, Linux, Python or related bioinformatics tools would be advantageous.
  • Some experience of mammalian cell culture would be useful but is not essential.
  • Some flexibility is required to process fresh surgical samples.

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The post is fixed-term for six months.

Please apply online through the University job pages http://www.jobs.cam.ac.uk/

For questions relating to the post, please contact Dr Thomas Nixon at trwn2@cam.ac.uk

Fixed-term: The funds for this post are available for 6 months in the first instance.

This appointment requires a Research Passport application.

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Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference RR50569 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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Skills

Single-cell Transcriptomics
Next-generation Sequencing
Library Preparation
Molecular Biology
Genomics
Tissue Dissociation
R
Python
Linux
Mammalian Cell Culture
Bioinformatics
Quality Control

Location

Cambridge, England, United Kingdom

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