University of Southampton
Research Fellow in Informatics and Genomic Medicine
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Research Fellow in Genomic Data Science
We are hiring a Research Fellow to join an interdisciplinary team of genomic informaticians, clinicians, bioinformaticians, and clinical data scientists working at the forefront of genomic data science for complex heritable conditions, primarily focused on inflammatory bowel disease.
The successful candidate will undertake research with the ultimate aim of improving personalised diagnostics through integration of clinical and genomic data.
Responsibilities
- Running pipelines for processing of next-generation sequencing data, alongside maintenance of these pipelines.
- Integrating genomic sequencing and other molecular datasets with high fidelity clinical data.
- Application and evaluation of methods for tasks such as data harmonisation, phenotype representation, genomic analysis, and patient or gene prioritisation.
- Working within research high-performance computing (HPC) environments to execute defined research workstreams, contribute to analytical strategy, and generate reproducible and clinically meaningful insights from large-scale genomic and health data.
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Research
- Process genomic and multiomic data (including quality control, pipeline maintenance, GenePy score generation) to facilitate personalised diagnostics.
- Perform and contribute to original methodological and analytical work.
- Execute defined components of collaborative research projects.
- Support the development of generalisable and scalable pipelines.
- Contribute to publications, collaborative webtools, presentations, and future funding applications.
- Provide day-to-day guidance to students with appropriate support and supervision.
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Note: Additional experience of large-scale clinical data and the use of LLMs across multiple data types and sources is desirable.
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