Scientist I

At DJS, we want to foster innovative scientists performing drug-discovery led by cutting-edge science. In this role, the successful candidate will develop knowledge across mechanistic biology, pharmacology, and early discovery with visibility across our portfolio of early discovery through to clinical-stage drug candidates. As such, this role will bring many career development opportunities. These are extended further by our unique position within AbbVie, which allows access into a much broader, world-leading drug development pipeline and learnings about broader pharmaceutical business.

Key Responsibilities

• Bringing energy, enthusiasm, and positivity to the company.
• Running cellular assays using cell lines and human primary cells to assess antibody efficacy, potency, and MOA, also to validate new targets.
• Performing critical laboratory experiments and analysis to support strategic decision-making within project teams.
• Engaging with the literature to better understand target biology and identify new assay methods.
• Developing their skill set to become a go-to expert for imaging-based assays.
• Day-to-day laboratory management as part of the team, e.g., maintaining a safe and clean working laboratory environment, re-ordering laboratory consumables.
• Mentoring junior scientists from the benchside in new and novel cell biology techniques and methodologies.
• Gathering, analyzing, and presenting data from a variety of sources to the wider team and organization.
• Contributing ideas and suggestions to all DJS programs.
• Developing and refining DJS internal laboratory capabilities.
• Critical and impartial review of self and peer-generated laboratory data.
• Maintenance of laboratory experimental records.

Qualifications

Required Attributes

• A PhD in Immunology or related field, or equivalent level of lab experience.
• Enthusiasm for and commitment to drug discovery and drug development research.
• Passion for in vitro immunology and translational biology.
• Proven expertise and experience in:
  • Human primary cell culture and in vitro and ex vivo assays.
  • Cell biology techniques including flow cytometry, ELISA (plate or bead-based), and fluorescence microscopy.

Desirable Skills

• Human primary cell antibody screening assay development (high and medium throughput).
• Experience in running human complex in-vitro models such as organ-on-a-chip models or organoids.
• Experience working with myeloid cells and performing differentiation assays.
• Fluorescent imaging image analysis and quantification (use of software such as Molecular Devices InCarta).
• Omics-based approaches such as RNA-seq.
• Evidence of excellent organizational and interpersonal skills including:
  • Ability to work both independently and as part of a team.
  • Ability to work efficiently with strong attention to detail.
  • Ability to build effective working relationships.
  • Laboratory method development.
  • Ability to work flexible hours when required.
  • Proven written and oral communicative ability.
  • Problem-solving skills.
  • Strong IT skills.

Additional Information

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit Equal Employment Opportunity Employer. US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: Reasonable Accommodations.

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