Insmed Incorporated
Scientist II In Vivo
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At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.
For patients, for each other, and for the future of science, we’re in. Are you?
About The Role
This is an outstanding opportunity for an experienced Scientist I or II to join the Insmed Innovation in vivo team and work closely with cross-functional teams situated in Babraham, Cambridge. Utilizing your in-depth knowledge, you will develop a vision on how the in vivo team can support all aspects of early target identification, target validation, and drug discovery programs. You will enjoy the fast pace of a growing biotech and thrive in a collaborative, passionate, multidisciplinary team with the mission of validating proprietary targets and contributing to drug discovery programs.
What You'll Do
- Use your expertise to support the design, implementation, and evaluation of in vivo studies (both in house as well as with CROs) to enable target identification, target validation and drug discovery across different projects.
- Plan and execute lab-based work followed by review and analysis of endpoint data including characterization of mouse models (both via image and behavior methods), efficacy studies and small-scale PK/PD studies, etc.
- Prepare study reports, summaries, and regulatory documents.
- Work with program leads and senior leadership team on overall in vivo project plans.
- Establish strong working relationships with vivarium staff, CROs and academic partners to collaborate and foster information exchange and to enable efficient execution of work packages consistent with program needs.
- Provide guidance and support for internal stakeholders on study design and data analysis and best location to execute these studies (either internal or by identifying suitable CROs to outsource these studies).
- Lead continuous improvement activities, apply problem solving skills to identify workflow efficiencies, and implement technology solutions to enhance processes.
- Work with internal stakeholders to ensure learning is captured and incorporated into processes and practices.
- Actively contribute to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared among the teams.
- Scientific coaching and mentorship of colleagues in our matrix-based team.
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Who You Are
Depending on whether you are applying for Scientist I or Scientist II, we would expect to see 4-5 years relevant experience working with in vivo models with both in-house and external partners. Expertise working in a neurodegenerative, neuroinflammatory, or cardiovascular disease area would be advantageous.
- Current UK Home Office Licence holder with hands on in vivo experience and experimental skills working with animal models. We will not be able to employ candidates who do not have a current licence or a dormant UK licence that can be reactivated.
- Experience in colony management to expand imported or newly generated models and generate experimental cohorts.
- Experience in planning and execution of efficacy studies, ideally with expertise in complex dosing routes such as IT, ICV, ICM and placement of cannulation for repeat dosing in mouse.
- Experience with mouse model characterization such as behavior phenotyping and/or image-based analysis.
- Experience in identifying key questions and requirements to effectively support projects from an in vivo perspective. Exercises judgment in selecting suitable animal models, methods, techniques and evaluation criteria for obtaining results.
- Understanding genome engineering and transgenic technologies for generating animal models would be advantageous.
- Expertise in tissue collection ideally for CNS related studies (e.g spinal cord, different brain regions, …) and sample processing (e.g fixation/embedding for histology) would be advantageous.
- Attention to detail, excellent analytical skills and an understanding of statistical methods, preparation of reports, summaries, electronic database entries and regulatory documents.
Life at Insmed
Our research site in Cambridge, UK is situated in brand new labs and offices at the Babraham Research Campus—a leading hub for bioscience innovation and collaboration. Our team of biologists, human geneticists, bioinformaticians, data scientists, computational and synthetic chemists bring together a wide range of technologies and modalities to deliver powerful new ways of treating serious diseases.
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At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.
Our Offerings Include
- Flexible work schedules with purposeful in-person collaboration
- Competitive retirement benefits, global equity awards, and participation in our Employee Stock Purchase Plan (ESPP)
- Career development through the Insmed Learning Institute, external programs, LinkedIn Learning, and role-specific training
- AI-powered and on-demand learning tools, including a digital assistant to help navigate internal resources
- Hybrid-friendly technology and IT support for seamless teamwork across locations and time zones
- Global recognition programs and Employee Resource Groups
Eligibility for specific programs may vary and is subject to the terms and conditions of each plan.
Current Insmed Employees: Please apply via the Jobs Hub in Workday.
Insmed Incorporated is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, age, or any other characteristic protected by law.
Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.
Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.
Applications are accepted for 5 calendar days from the date posted or until the position is filled.
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