ICON Strategic Solutions
Senior Clinical Pharmacologist
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ICON plc
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
We are currently seeking a Senior Clinical Pharmacologist (Director, Clinical Pharmacology) to join our growing client-dedicated team at ICON.
This is a unique opportunity to become an embedded strategic partner within a leading global pharmaceutical organization, influencing development programs from early research through registration.
As a Senior Clinical Pharmacologist, you will join a highly collaborative client-dedicated team, partnering with scientific and clinical leaders to support clinical pharmacology strategy across programs from early development through registration. You will apply your expertise in clinical pharmacology, biopharmaceutics, and model-informed drug development to drive informed decision-making and accelerate the development of innovative therapies.
What You Will Do
- Lead clinical pharmacology strategies across early and late-phase drug development programs.
- Apply model-informed drug development principles to support dose selection, patient population strategy, biomarkers, and endpoint optimization.
- Partner with Pharmacometricians to develop and execute PK/PD modeling and simulation strategies.
- Contribute to translational medicine initiatives, preclinical study design, and First-in-Human (FIH) studies, including SAD and MAD dose selection.
- Provide clinical pharmacology expertise to cross-functional teams, governance discussions, and key development decision points.
- Support regulatory submissions and responses to health authority queries.
- Drive collaboration across preclinical, clinical, regulatory, and quantitative sciences teams to advance development programs.
- Stay current with emerging innovations in clinical pharmacology, pharmacokinetics, biopharmaceutics, and quantitative drug development.
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You Will Have
- PhD in Biological Sciences, Bioengineering, Pharmacology, Pharmaceutical Sciences, or a related discipline.
- Extensive experience within clinical pharmacology, pharmaceutical development, or a related industry setting.
- Strong hands-on expertise in clinical pharmacology strategy, study design, PK/PD modelling, and quantitative data interpretation.
- Deep understanding of model-informed drug development and its application across the drug development lifecycle.
- Experience supporting translational medicine strategies and early clinical development programs, including FIH studies.
- Strong knowledge of innovative approaches in clinical pharmacokinetics, biopharmaceutics, and PK/PD modelling.
- Comprehensive understanding of global drug development and regulatory requirements.
- Excellent communication and stakeholder management skills, with the ability to influence and build alignment across scientific and business functions.
- Proven ability to lead complex scientific discussions and contribute to strategic development decisions.
What ICON Can Offer You
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
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Our Benefits Examples Include
- Various annual leave entitlements
- A range of health insurance offerings to suit you and your family’s needs.
- Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
- Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
- Life assurance
- Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values.
We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply.
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