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ICON plc

Senior Manager, Clinical Data Management

Johannesburg
Posted about 18 hours ago
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Clinical Data Management Lead

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients, and suppliers.

As a Senior Manager, Clinical Data Management at ICON, you will be client dedicated, serving as the primary data lead across global clinical trials and partnering closely with sponsors to drive high-quality, regulatory-compliant data delivery from study start-up through database lock.

Key Responsibilities

  • Acting as the primary data lead within cross-functional study teams and sponsor partnerships
  • Driving study start-up activities including EDC build, system integrations, UAT, and key data management deliverables
  • Overseeing data review, reconciliation, vendor management, and database lock activities
  • Ensuring compliance with CDISC standards, ICH-GCP requirements, and regulatory expectations
  • Identifying and mitigating risks while driving continuous improvement and operational excellence

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Why you're a good match

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You Will Have/Be:

  • Bachelor's degree in Life Sciences, Health Sciences, or a related discipline
  • 6+ years of Clinical Data Management or Clinical Data Science experience within a CRO or pharmaceutical environment
  • Proven experience leading studies across the full clinical trial lifecycle
  • Experience as a primary Data Lead on complex studies and/or extensive hands-on data review and reconciliation experience across EDC, vendor, eCOA, IRT, and SAE data
  • Strong vendor oversight and stakeholder management experience
  • Hands-on experience with EDC systems, with Veeva EDC preferred
  • Knowledge of CDISC standards, including SDTM
  • Strong understanding of clinical trial processes, regulatory requirements, and ICH-GCP
  • Excellent communication, problem-solving, and project leadership skills

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

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Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

  • Competitive base salary and performance-related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply.

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Skills

Clinical Data Management
Clinical Data Science
EDC systems
Veeva EDC
CDISC standards
SDTM
ICH-GCP
Vendor management
Database lock
System integrations
UAT
Data reconciliation
Risk mitigation
Stakeholder management
Project leadership
Regulatory compliance

Location

Warsaw, Masovian Voivodeship, Poland

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