ABOUT THE ROLE

AmpliSynth is developing the next-generation of DNA synthesis automation. We are seeking our first engineering hire to lead the design, development, and deployment of this instrument, taking it from initial concept through prototyping, validation, and delivery to customers. We are based in London, United Kingdom. Work is hybrid, but expected in person when needed.

This is a unique opportunity to become a founding member of the team and take ownership of a core product that sits at the intersection of biology, automation, electronics, software, and mechanical engineering. You will work directly with the CEO and CSO to integrate experimental requirements into robust workflows capable of executing complex DNA synthesis workflows both internally, and for partners.

You will be responsible for designing, prototyping, testing, and iterating the instrument architecture, making pragmatic engineering decisions that balance performance, reliability, speed of development, and cost.

Key responsibilities

• Lead the design and hardware implementation of systems for biochemical workflows.
• Translate biological workflows into hardware and software requirements.
• Design and prototype subsystems including thermal control, liquid handling and motion systems.
• Integrate prototypes with commercially available liquid handlers, starting on the Opentrons and scaling to Hamilton/Tecan/Beckman platforms.
• Work closely with two founders to develop experimental methods and validate instrument performance.
• Manage external suppliers, manufacturers, and specialist contractors where required.
• Work with design partners to improve the quality and experience of SynthBox.
• Support pilot deployments and customer handover of early systems.
• Build and lead the future engineering function as the company grows.