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Senior / Principal Bioinformatician

London
Posted about 19 hours ago
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Your new company

Join a global biopharmaceutical organisation dedicated to transforming patient outcomes across multiple disease areas. You'll be part of a science-driven environment that values innovation, collaboration, and meaningful impact and work with highly experienced colleagues.

Your new role

This is a long term contract role (initially 1 year but likely to extend) within a well-established team where you will be reporting into senior bioinformatics leadership. The company has a collaborative and innovative atmosphere, where you will be supporting multiple projects within translational and clinical development across several therapy areas.

The role is hybrid, with approximately 3 days per week from home, though this can be negotiable for the right candidate.

The role can be at either Senior Bioinformatician or Principal Bioinformatician grade and you will be working on drug development projects, playing a key role in generating biological insights from clinical stage omics data to support decision making across the therapeutic portfolio.

Major responsibilities will include:

  • Processing, analysing, and interpreting multi-omic (RNAseq, NGS, proteomic, etc) datasets from clinical studies
  • Deriving mechanistic, biological, and treatment related insights from patient-level data
  • Developing and optimising analysis methods, pipelines, and computational workflows
  • Ensuring reproducibility and best practice documentation for code and analyses
  • Drafting high quality reports and contributing to scientific publications
  • Applying SOTA (state-of-the-art) tools for functional interpretation (e.g., pathway enrichment)
  • Integrating omics outputs with clinical variables to enhance understanding of drug effects
  • Operating autonomously while collaborating with cross-functional scientific teams

Reasons to use Rodeo

I’m in my final year doing Economics and I don’t know whether to apply for grad schemes now or do a masters first. What do you think?

Honest answer — it depends on where you want to end up. A lot of top grad schemes (Big 4, civil service, banking) don’t need a masters. Let’s look at the ones you’d be competitive for now, and we can decide if a masters actually adds anything.

Also worth knowing: most autumn 2026 applications are open now. Timing matters more than you think.

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Grad scheme, placement, apprenticeship? Not sure what you want yet — that's fine. Your agent talks it through with you and turns "I have no idea" into a shortlist.

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Graduate Consultant — 2026 Scheme

PwC·London, UK
£35,000/yr

Why you're a good match

Strong

Your economics background and your summer at a regional bank line up with what PwC looks for on the consulting scheme. Applications close in four weeks.

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Why you're a good match

You’ve got the grades and the economics background, and your bank internship is exactly the experience this scheme looks for. Apply soon — deadlines close within the month.

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Strong

Experience fit

Your summer at the bank plus your econometrics coursework map directly to the day-one responsibilities on this scheme — client modelling, market briefings, and deal support.

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Strong

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What you'll need to succeed

A strong candidate will bring experience in clinical bioinformatics along with:

  • An MSc / PhD (or equivalent experience) in bioinformatics, computational biology, statistical genetics, biology, or a related subject
  • Good expertise in analysing bulk and single-cell RNA-seq from complex or clinical studies, with a significant preference for candidates who have done this in an industry (pharma, biotech, CRO) setting
  • Experience with multi-omics integration, functional interpretation, and pathway analytics
  • Strong computational skills, including HPC, cloud platforms, and containerisation tools
  • Proficiency in R and other commonly used bioinformatics programming languages
  • Solid grounding in statistics, data mining, and biological data visualisation
  • Ability to clearly communicate findings to both expert and non-expert audiences

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What you'll get in return

As well as an excellent opportunity to progress and develop your career within an innovative and collaborative work environment you'll be making a significant impact on the next generation of medicines and the patients they treat.

You'll also have plenty of flexible working options and a generous pay package.

What you need to do now

If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.

If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion on your career.

Keywords: senior, principal, bioinformatics, bioinformatician, drug, discovery, pharmaceutical, biotech, clinical, principal, omics, RNAseq, single-cell, computational, analysis, pipeline, genetic, genomics, proteomics, epigenetic, spatial, data, integration, pathways, enrichment, causal, mechanisms, disease, biology, statistics, visualisation, programming, R, immunology, neuro, CNS, oncology, cancer, inflammation, respiratory

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Skills

Bioinformatics
RNA-seq
Single-cell RNA-seq
Multi-omics integration
R
HPC
Cloud platforms
Containerisation
Statistics
Data mining
Biological data visualisation
Pathway enrichment
NGS
Proteomics
Computational workflows
Clinical bioinformatics

Location

London, England, United Kingdom

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