Optibrium
Senior / Principal DevOps Engineer

How your CV stacks up
Upload your CV to see how well it fits this job role
?%
Principal DevOps Engineer
Optibrium is a technology company developing innovative software and AI solutions for drug discovery. Our solutions enable industry-leading drug research for our worldwide customer base, including many top-10 pharma and innovative biotech companies. Founded in 2009, Optibrium’s headquarters is in Cambridge, UK, and Optibrium has regional offices in Boston, MA, and San Francisco, CA, USA.
Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis. Optibrium’s lead product, StarDrop™, is a comprehensive suite of integrated software with a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through to predictive modelling and decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. The Company’s new Augmented Chemistry™ products and services deliver ground-breaking artificial intelligence technologies that continuously learn from all available data to supplement researchers’ experience and skills.
Main Responsibilities
As a Principal DevOps Engineer at Optibrium, you will:
- Maintain and extend our existing AWS cloud-based infrastructure and the products and services it supports efficiently and effectively
- Minimise any downtime and ensure cloud-based data-recovery protocols are up-to-date and working effectively
- Ensure all cloud infrastructure, products, and services are fully patched/updated to provide the best defence against critical data loss/exfiltration (cyber-attacks, disaster events, etc.)
- Ensure our cloud-based disaster recovery plan is fully up-to-date and regularly reviewed
- Coordinate with the security working group to ensure that policies and procedures relating to the cloud infrastructure (e.g., our disaster recovery plan) remain up-to-date and regularly reviewed and are aligned/maintained to IS27001 standards
- Mentor and develop members of the team
- Work with the wider organisation to instill DevOps best practices amongst the wider organisation
Reasons to use Rodeo
I’m in my final year doing Economics and I don’t know whether to apply for grad schemes now or do a masters first. What do you think?
Honest answer — it depends on where you want to end up. A lot of top grad schemes (Big 4, civil service, banking) don’t need a masters. Let’s look at the ones you’d be competitive for now, and we can decide if a masters actually adds anything.
Also worth knowing: most autumn 2026 applications are open now. Timing matters more than you think.
Start with a chat, not a search bar
Grad scheme, placement, apprenticeship? Not sure what you want yet — that's fine. Your agent talks it through with you and turns "I have no idea" into a shortlist.
Graduate Consultant — 2026 Scheme
Why you're a good match
StrongYour economics background and your summer at a regional bank line up with what PwC looks for on the consulting scheme. Applications close in four weeks.
See breakdownIt searches the market for you
Every day your agent scans the market matching roles against what actually matters to you, not just keywords on a CV.
Why you're a good match
You’ve got the grades and the economics background, and your bank internship is exactly the experience this scheme looks for. Apply soon — deadlines close within the month.
Experience fit
Your summer at the bank plus your econometrics coursework map directly to the day-one responsibilities on this scheme — client modelling, market briefings, and deal support.
Only hits
No noise. No "maybe this fits." Just roles with a clear explanation of why they're right — and where to focus when applying.
Experience and Skills
You will bring:
- A deep understanding of Docker build and ECR distribution strategies
- Advanced experience developing Kubernetes applications with deployment via Helm charts
- Experience developing Infrastructure as Code with Terraform
- Experience developing in Python
- Working knowledge of authentication and authorisation systems such as SSO, OAuth, etc.
- Understanding of AWS resources, including: EKS, EC2, S3, IAM, SSO, VPC, etc.
- Development of pipelines as code using Jenkins and GitHub Actions
- Previous experience with automated integration testing in CI/CD pipelines using Behave, Flask 8, and Coverage
- Advanced AWS monitoring, maintenance, and debugging skills
- Ability to prioritise, coordinate, and delegate in accordance with business priorities whilst progressing the DevOps Roadmap
- Ability to take ownership and drive initiatives through to completion


Get help with your application
Your very own career expert that helps elevate your application to the next level.
Background
Founded in 2009, Optibrium has headquarters in Cambridge, UK, with offices in Boston, MA, and San Francisco, CA. Optibrium continues to develop new products and research novel technologies to improve the drug discovery process. Optibrium works closely with its broad range of customers and collaborators, including leading global pharma, agrochemical, and flavouring companies, biotech, and academic groups.
Optibrium is an established business with strong revenues and a positive cash position. We have recently secured significant PE investment, which will be used to expand our business through exciting new innovations, markets, and, most importantly, people. Our culture is entrepreneurial – we love fostering ideas from every team member, and our daily coffee breaks have become a forum for creative thinking. Taking time to listen to and learn from each other ensures we are all working towards a collective purpose.
“It took my CV and asked me questions relevant to understanding what kind of jobs to suggest for me. Suggestions were almost perfect. Jobs were exactly what I’ve been looking for.”
Jessica, London
Location