Senior Protein Crystallisation Scientist

Company: BioOrbit
Location: London
Type: Full-time

Application Note: Only applicants with the right to work in the UK, without needing visa sponsorship now or in the future, will be considered. Please submit both a CV and cover letter – applications without both won't be reviewed.

About BioOrbit

BioOrbit is pioneering space-enabled pharmaceutical development. Utilising the unique environment of microgravity BioOrbit is crystallising biologics and other complex medicines at scale, unlocking novel drug formulations that improve patient access and comfort.

Role Overview

We are seeking an experienced protein crystallisation scientist to help prove BioOrbit’s core scientific propositions and develop novel crystal products. You will design and execute experiments that test whether selected proteins can be crystallised into forms that create measurable pharmaceutical advantages, both with our reactor on Earth and in space.

Key Responsibilities

• Run and optimise protein crystallisation screens to identify robust crystallisation conditions. This requires analysing complex experimental datasets to generate insight and guide iterative development.
• Collaborate with external partners (CROs, academic groups) for specialised analyses.
• Design and execute experiments that investigate BioOrbit’s core value proposition hypotheses for internal and external crystal products, e.g. scaling to high-concentration formulations and analysing physicochemical parameters such as viscosity.
• Characterising particle systems, including particle size distribution, crystal morphology, polymorphism, purity, aggregation, and stability.
• Translate molecular insights into parameters and constraints for reactor and process design.
• Work closely with bioprocess engineers to align crystallisation science and process implementation.
• Contribute to documentation, data integrity, and scientific communication internally and externally.
• Mentor junior scientists as the team grows.