Helical
Senior Scientist (Comp. Bio/ML)
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About the Role
We’re looking for a Senior Computational Scientist to help translate our foundation models into impactful, real-world discovery workflows. In this role, you’ll provide scientific leadership across model evaluation and applied use cases, ensuring our work stays grounded in the most relevant challenges in drug development and translational research.
Responsibilities
- Join as a senior individual contributor, reporting to the Head of Computational Biology, with the opportunity to grow into management as the team scales.
- Act as a key scientific partner to our research team.
- Mentor and support junior colleagues.
- Work closely with Product and Business Development to turn cutting-edge biology + ML into deliverables that matter for customers.
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Requirements
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- PhD in Computational Biology, Machine Learning, Bioinformatics, or a related field, with a strong focus on early drug discovery + ML, and 2+ years of industry (non-academic) experience OR MSc in a relevant field and 5+ years of industry experience applying ML to early drug discovery problems
- Strong understanding of ML/AI methods for biological data (e.g., transformers, VAEs, diffusion models, classical ML)
- Hands-on experience with modern ML frameworks such as PyTorch (or equivalent)
- Leadership experience with small teams to work towards defined roadmaps or projects
- Excellent communication skills — able to translate complex science into clear, actionable insights for technical and non-technical stakeholders
- Comfortable in a fast-paced, high-iteration environment, moving quickly from prototype → experiment → insight
- Strong passion for building at the intersection of biology and machine learning
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