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Senior Scientist in Trace Analysis Mass Spectrometry

Macclesfield
Posted about 22 hours ago
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About The Company

At AstraZeneca, we are more than just a leading pharmaceutical company; we are a place where innovation and collaboration thrive. Pharmaceutical Technology and Development (PT&D) are the bridge, which turns brilliant science into actual medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices required to support new medicines - from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture. In Chemical Development we believe that nothing is impossible, and we are determined to push the boundaries of science to deliver medicines to our patients.

Responsibilities

  • You will be part of a team of scientists providing advanced analytical support to AstraZeneca, Macclesfield, with a focus on the application of mass spectrometry to achieve quantification of trace impurities and some characterisation to develop pharmaceutical products.
  • You'll contribute to method review, technical data review and method development.
  • You'll use skills in separation science, mass spectrometry, and sample preparation approaches to enhance project understanding.
  • Working closely with external partners and across the organisation will be key.
  • Supporting science capability will be an opportunity to impact across the organisation and partners, as will communicating data effectively to diverse audiences.
  • Your work will adhere to Safety, Health & Environment (SHE) guidelines and compliance standards like Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP).

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Graduate Consultant — 2026 Scheme

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Requirements

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  • A relevant scientific degree with significant mass spectrometry experience.
  • Ability to develop and review mass spectrometry methodologies to quantify trace analysis components and to assist structure confirmation/elucidation of small molecules.
  • Practical experience in the operation and data interpretation for a range of mass spectrometry systems and some knowledge of trace analysis challenges.
  • Good communication and influencing skills across disciplines and cultures both internally and externally.
  • Knowledge of advanced automated sample preparation techniques.
  • An appreciation of advanced mass spectrometry techniques and challenges.

Benefits

  • Competitive salary and benefits
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Skills

Mass Spectrometry
Trace Analysis
Separation Science
Sample Preparation
Method Development
Data Interpretation
GMP
GLP
Small Molecule Characterization
Structure Elucidation

Location

Macclesfield, England, United Kingdom

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