Company Description

Guilford Street Laboratories (GSL), a UCL spin-out, specializes in supporting clients through machine learning-driven mass spectrometry services. We deliver precise and sensitive biomarker panels focusing on proteins, lipids, and metabolites.

Role Description

This is a full-time, on-site role for a Senior Scientist in our Discovery CoreLabs team, located in Greater London. The Senior Scientist will be responsible for designing and conducting experiments, analysing complex datasets, developing biomarker panels, and contributing to research-focused initiatives. The role involves collaboration with cross-functional teams, overseeing laboratory operations, and ensuring adherence to best practices and compliance requirements. The position also requires mentoring junior staff and presenting findings to stakeholders.

• Lead on client projects within GSL’s Discovery CoreLabs program
• Validate targeted proteomic, lipidomic, and metabolomic assays to clinical standard (GCLP, CLIA, etc.)
• Independently apply scientific principles to achieve project objectives, including the design and execution of complex experiments, and analysis and interpretation of data under limited supervision.
• Assess the viability and feasibility of new assays.
• Execute project deliverables for biomarker studies in clinical trials by project scope of work and within sponsor-specific timelines.
• Manage day-to-day operational aspects of clinical biomarker projects.
• Assist in preparation and adherence to trial documents, i.e., Project Protocols, Data Transmittal Forms, etc.
• Ensure project documentation is complete, current, and stored appropriately.
• Manage key documents/processes, i.e., Project Management Plan, Communication Plan, Escalation Plan, Risk Management Plan, and appropriate Clinical Trial Management Systems (CTMS).
• Identify scope-out quests – working with appropriate team(s) to revise work orders to meet changing needs and requirements.
• Prepare metrics reporting for client and senior management.
• Manage Core Lab Resources and ensure timely delivery of analysis.
• Working alongside the head of commercial – support of pre-sales process – methodologies, procedures & pipelines.
• Creating and contributing to Standard Operating Procedures of the overall service, and individual projects.
• Direct Customer engagement.
• Liaise with external study teams to ensure smooth delivery of project metrics – this may include attendance at progress meetings as required.
• Some domestic and international travel will be required.
• Contribute to laboratory duties to maintain smooth laboratory operation.
• Troubleshoot equipment issues.
• Adhere to laboratory safety protocols and human tissue sample handling procedures.
• Carry out any other duties as are within the scope, spirit, and purpose of the job as requested by the Line Manager.