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Senior Statistical Analyst
ICON
Full-time
UK, Reading
11h ago
JR158816 Senior Statistical Analyst
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
Senior Statistical Analyst - Real World Evidence
We are currently seeking a Senior Statistical Analyst to join our Real World Evidence (RWE) team. This position offers an exciting opportunity to work on observational research studies, real-world data analyses, health outcomes research, and epidemiology projects that help generate evidence to support healthcare decision-making.
As a Senior Statistical Analyst, you will play a key role throughout the project lifecycle, from study design and statistical planning through to analysis, reporting, publication and client interaction. The role requires strong technical expertise in SAS programming, statistical methodology, and the interpretation of complex healthcare datasets.
What You Will Be Doing
- Support study conception, design, and protocol development for real-world evidence and observational research projects.
- Contribute to study start-up activities, including review and development of protocols, case report forms, and statistical methodologies.
- Write statistical methods sections of study protocols and develop statistical analysis plans.
- Perform sample size and power calculations.
- Review database specifications and participate in data review activities.
- Develop table, listing and figure shells and programming specifications.
- Lead the review and validation of raw and derived variables.
- Create and maintain derived datasets using SAS programming.
- Conduct statistical analyses using appropriate methodologies, including advanced and specialized statistical techniques such as longitudinal analyses, repeated measures, survival analyses, and other complex modelling approaches.
- Develop and validate SAS programs, macros, tables, listings, figures, and project deliverables.
- Lead quality control activities throughout programming and analysis processes.
- Manage and review internal and external data transfers.
- Produce project reports, statistical outputs, visualizations, tables and graphs for client delivery.
- Contribute to manuscripts, abstracts, conference presentations and peer-reviewed publications.
- Write methods and results sections for final reports and scientific publications.
- Communicate directly with clients, investigators and cross-functional teams regarding project deliverables and statistical requirements.
- Represent Statistical Analysis in proposal development and RFP activities.
- Participate in department initiatives, process improvements, SOP development and training activities.
- Deliver internal technical presentations and contribute to knowledge sharing within the team.
- Attend departmental meetings and support broader Real World Evidence research activities.
Reasons to use Rodeo
I’m in my final year doing Economics and I don’t know whether to apply for grad schemes now or do a masters first. What do you think?
Honest answer — it depends on where you want to end up. A lot of top grad schemes (Big 4, civil service, banking) don’t need a masters. Let’s look at the ones you’d be competitive for now, and we can decide if a masters actually adds anything.
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Graduate Consultant — 2026 Scheme
Why you're a good match
StrongYour economics background and your summer at a regional bank line up with what PwC looks for on the consulting scheme. Applications close in four weeks.
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Why you're a good match
You’ve got the grades and the economics background, and your bank internship is exactly the experience this scheme looks for. Apply soon — deadlines close within the month.
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Your Profile
To be successful in this role, you will possess a strong statistical and programming background, together with experience working with healthcare, clinical, observational or real-world data.
Required Qualifications And Experience
- Master's degree or PhD in Statistics, Biostatistics, Epidemiology, Mathematics, Data Science, Public Health, or a related quantitative discipline.
- Significant experience within the pharmaceutical, biotechnology, CRO, healthcare research, or Real World Evidence environment.
- Advanced SAS programming experience is essential, including development of datasets, statistical analyses, macros, tables, listings and figures.
- Strong understanding of statistical methodologies and their practical application to healthcare and observational data.
- Experience developing Statistical Analysis Plans (SAPs) and analysis specifications.
- Knowledge of observational study design, epidemiology, health outcomes research, registries, claims databases, electronic health records, or other real-world data sources is highly desirable.
- Experience applying statistical techniques such as regression modelling, survival analysis, repeated measures analysis and other advanced methods.
- Ability to independently manage statistical deliverables while collaborating effectively within multidisciplinary teams.
- Strong written and verbal communication skills with the ability to explain complex statistical concepts to both technical and non-technical audiences.
Preferred Experience:
- Experience within a Real World Evidence, Health Economics & Outcomes Research (HEOR), Epidemiology, or Data Analytics team.
- Experience authoring publications, abstracts, or conference presentations.
- Proficiency in additional programming languages such as R is advantageous.
Why Join the Real World Evidence Team?
You will be part of a collaborative team delivering high-impact research that helps shape healthcare decisions and improve patient outcomes globally. This role provides the opportunity to work on diverse, scientifically rigorous projects while developing deep expertise in real-world data, advanced analytics and evidence generation.
Please note: Strong SAS programming experience is a core requirement for this position and will be a key focus throughout the selection process.
What ICON Can Offer You
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.


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In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our Benefits Examples Include
- Various annual leave entitlements
- A range of health insurance offerings to suit you and your family’s needs.
- Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
- Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
- Life assurance
- Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply
ICON
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