The Institute of Cancer Research
Analytical Scientist in Data Science
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Data Scientist / Bioinformatician Fixed-Term Role (2 Years) – Full-Time (35 Hours/Week)
Accountable to: Dr Ros Cutts, Senior Bioinformatician (Liquid Biopsy), ICR/Primary Care University Partnership Centre
About the Role
The Molecular Oncology Laboratory at the Institute of Cancer Research (ICR) is seeking an Experienced Data Scientist/Bioinformatician with state-of-the-art machine learning (ML) expertise to advance precision medicine in breast cancer treatment.
In this scientific research role, you will:
- Contribute to cutting-edge biomarker research and clinical data analysis within a team focused on overcoming treatment resistance in breast cancer.
- Develop novel statistical and machine learning approaches to analyse high-dimensional biological datasets, including metadata derived from circulating free DNA (cfDNA) and alternative assays.
- Collaborate with a multidisciplinary team—spanning oncologists, computational scientists, and liquid biopsy researchers—to translate data into personalised breast cancer therapy strategies.
- Work closely with Dr Ros Cutts to integrate computational methods into clinical research frameworks.
Key Responsibilities
Data Science & Bioinformatics
- Design, implement, and validate statistical models and machine learning algorithms tailored to omics data and clinical datasets.
- Process, clean, mining, and integrate multi-layered bioinformatics datasets (e.g., RNA-sequencing, cfDNA, proteomics).
- Drive novel analysis pipelines for incorporating liquid biopsy data (e.g., cfDNA-derived traits) into precision medicine workflows.
Collaboration & Project Delivery
- Work across research teams (academic and clinical) to define research questions and translate findings into actionable biomarker-driven strategies.
- Publish results in peer-reviewed journals and disseminate outcomes at national/international conferences.
- Support the lab’s external biomarker validation programmes, including clinical trial activities.
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Innovation & Growth
- Document and optimise workflows, ensuring reproducibility and scalability of computational methods.
- Stay current with scientific advances in AI-driven clinical decision support while translating them for cancer precision therapeutics.
** Requirements**
Essential Criteria
- Doctoral qualification (or equivalent experience) in bioinformatics, computational biology, statistics, data science, or closely related field.
- Proven expertise in machine learning, including familiarity with classification, clustering, time-series, and network-based models in a biological context.
- Hands-on experience using major Python/R scientific frameworks and tools such as scikit-learn, TensorFlow/Pytorch, Bioconductor/GATK, or liquid biopsy analysis platforms.
- Familiarity with next-generation sequencing data, single-cell analysis, and/or smartNIPT (non-invasive prenatal testing) methodologies.
- Strong linux/scripting proficiency and computational genomics capabilities (e.g., variant calling, BioSystems analysis).
- Ability to archive datasets in compliance with UK data protection regulations.
Desirable Qualifications
- Experience with blockchain or federated learning approaches for data decentralisation.
- Prior hands-on work integrating AI/ML into real-world clinical settings (preferably oncology-focused).
- Abilities to apply Bayesian frameworks or reinforcement learning paradigms to analyse dynamic bioinformatic pipelines.
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Benefits
- Generous salary range: £39,805–£50,862 p.a. (commensurate with experience).
- Cultural and professional development support (all-expenses-paid conferences, short courses, professional memberships).
- World-class facilities and international funding for experimental projects.
- Access to professional networks with leaders in precision oncology.
- Comprehensive pension, annual leave, and childcare subsidies (up to 80% contribution for ICR staff towards local facilities).
- Inclusive working environment, championing diversity across all dimensions.
CRITICAL NOTES
- This role is eligible for ICR Sponsorship for the Home Visa process if this is your first UK visa; some relocation support will be provided.
- Offers of employment and namely initial salary points on the scale are subject to Skills/Experience & Vetted Salary Negotiation.
- The role is fixed-term for 24 months, commencing on negotiable start date.
Equality & Inclusion Disclaimer The Institute of Cancer Research is a values-based organisation and embraces diversity and equality. Your application is judged on motivation and potential, without barriers related to background or life-stage.
For further details on our commitments visit ICR Diversity Programme policy.
Closing Date: Wednesday 8th July 2026. Applications welcome until this date. We encourage early submission. Applications are confidential.
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