UCB
Drug Metabolism and Pharmacokinetics (DMPK) Lead/Director
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DMPK Lead/Director – Drug Metabolism and Pharmacokinetics
Make your mark for patients
We are looking for a DMPK Lead/Director, who is strategic, collaborative, and scientifically driven, to join our Research & Development team, based in Braine-L’alleud (Belgium) or Slough (UK), with a planned relocate to Windlesham from 2027.
About the Role
In this Director-level position, you will provide scientific leadership and expertise in Drug Metabolism and Pharmacokinetics (DMPK), spanning global discovery and development programs. Your responsibility includes defining and delivering DMPK strategies across the full lifecycle—from early research through clinical development and registration—to support candidate selection, risk assessment, and patient-focused innovation.
You will play a critical role in enabling the transition from discovery to clinical success across diverse therapeutic modalities.
Who You’ll Work With
- Collaborate with multidisciplinary project teams in R&D, working alongside experts in:
- Toxicology
- Clinical pharmacology
- Drug design
- Translational sciences
- Partner with the global DMPK community to drive scientific excellence and best practice.
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What You’ll Do
- Lead DMPK strategy across discovery and clinical development programs
- Design and interpret PK, PK/PD, toxicokinetic, ADME, and translational studies
- Influence:
- Compound design
- Candidate selection
- Risk mitigation
- Predict:
- Human pharmacokinetics
- Dose requirements
- Drug-drug interaction risks
- Contribute to modelling and simulation, including PBPK activities
- Author DMPK sections for regulatory submissions and internal documents
- Serve as a DMPK expert for due diligence evaluations of external opportunities
- Provide scientific mentoring and coaching to junior staff
Interested?
For this role, we are seeking:
✔ PhD (or equivalent) in Pharmaceutics, Pharmacology, DMPK, or a related discipline ✔ Significant industrial DMPK experience across discovery and development ✔ Strong expertise in ADME, PK studies, and human PK prediction ✔ Knowledge of regulatory requirements and submission processes ✔ Experience with modelling and simulation (preference for PBPK) ✔ Proven ability to work effectively in global, cross-functional teams
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Are you ready to ‘go beyond’ and create value for patients? If this sound like you, we’d love to hear from you!
About Us
UCB is a global biopharmaceutical company, with a focus on neurology and immunology. We are powered by more than 9,000 people worldwide, inspired by patients and driven by science.
Why Work With Us?
- Create meaningful impact—we Go Beyond to create value that matters.
- Supportive and forward-thinking culture where everyone is included, respected, and empowered to excel.
- Freedom to grow and carve your own career path.
- Innovative workplace: Hybrid-first approach, with 40% office presence (unless stated otherwise).
- Equal opportunity employer—all decisions are made based on merit.
“Should you require any adjustments to our process to assist you, contact:** EMEA-Reasonable_Accommodation@ucb.com (only for accessibility requests).
Join us today and make your mark for patients.
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