GSK
Executive Medical Director, Clinical Development Lead - Oncology
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Executive Medical Director, Clinical Development Lead - Oncology
Clinical Development Lead – Oncology
Business Introduction
At GSK, we are driven by bold ambitions to positively impact the health of 2.5 billion people by the end of this decade. Our Research & Development (R&D) teams focus on discovering and delivering vaccines and medicines by combining deep immune system understanding with cutting-edge technology to transform lives.
We foster a culture characterised by:
- Patient-centred ambition
- Accountability for measurable impact
- An unwavering commitment to integrity This ensures we strategically direct efforts toward assets that address unmet patient needs with high probability of commercial success. Through science, technology, and talent, we unite in our mission to stay ahead of disease collectively.
Discover more about GSK’s approach to R&D
Position Summary
The Opportunity
Cancer remains a formidable challenge, but so is GSK’s resolve to transform patient outcomes through innovative science, bold ambition, and strategic partnerships across the healthcare ecosystem.
Focusing on high-unmet-need cancers, GSK drives progress by leveraging deep disease biology insights and discerning scientific choices.
As the Clinical Development Lead (CDL) – Oncology, you will serve as the enterprise clinical strategy leader for an oncology asset, shaping the clinical strategy, scientific narrative, and decision framework across the full asset lifecycle.
Primary Responsibilities
You will:
- Own the clinical roadmap, ensuring alignment with the asset’s strategic vision.
- Act as the clinical authority, bridging scientific insight, development innovation, and decision velocity across the organisation.
- Represent Clinical Development in both internal and external settings.
- Ensure end-in-mind reasoning in development plans, integrating:
- Target selection
- Regulatory positioning
- Commercial readiness
- Advance a modelling framework that enhances:
- Speed
- Precision
- Decision quality
This role embraces candidates with medical or non-medical backgrounds. A formal qualification (MD, PharmD, PhD, or equivalent) is required, with an MD or clinical doctorate preferred. However, it isn’t qualifications, but depth of oncology expertise and enterprise-level leadership, that matter most.
In This Role You Will...
Strategic and Governance Leadership
Define and own all aspects of the asset’s clinical strategy, ensuring coherence and differentiation through the entire lifecycle. Responsibilities include:
- Integrating the benefit–risk framework, ensuring alignment between clinical intentions, safety insights, and decision frameworks across:
- Study design
- HCP engagement
- Regulatory interactions
- Lead programme governance discussions with leadership teams, translating clinical data and benefit-risk assessments into strategic recommendations for:
- Portfolio prioritisation
- Resource allocation
- Represent the asset clinically both internally and externally, building consensus on high-value, data-driven clinical rationales.
Innovation-Driven Development
- Champion a patient-centric development model, collaborating acfunctionally from:
- Medical Affairs
- Integrated Evidence
- Regulatory Affairs
- Commercial
- Embed AI-driven insights, data analytics, and emerging technologies into clinical strategy and programme execution to enhance speed and decision quality.
- Key example: Leverage emerging data platforms to evaluate unmet patient needs or prioritise sub-populated-based submissions.
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People Leadership and Growth
- Develop and mentor teams focused on clinical development excellence, enhancing their capability in:
- Precision medicine
- Regulatory strategy
- Cross-functional decision-making
- Guide succession planning and capability development for GSK’s evolving capability, including:
- PRISM (GSK’s Precise Vision for streamlined, adaptive programmes)
- Oversight of Senior Scientists within the asset team, ensuring aligned development goals.
External Engagement
- Default voice of Clinical Development for interactions with:
- Health Authorities (e.g., FDA, EMA, NICE)
- External Advisory Boards
- Steering committees
- Independent Data Monitoring Committees (IDMCs)
- Alliance partners
- Ensure clear, scientifically sound communication across all external engagements, reflecting your ability to:
- Interpret data
- Identify trends
- Provide strategic guidance for external stakeholders.
Responsibilities
This enterprise-level career accelerator encompasses a broad range of responsibilities:
1. Clinical Strategy and Governance
- Own the asset narrative as the primary advocate for Clinical Development insights, ensuring strong internal alignment and relationship-building with:
- Portfolio selection teams
- Strategic investment groups
- Leadership board-level decision teams
- Provide strategic clarity for the Clinical Development Plan (CDP), ensuring defined scientific pathways are aligned with operational execution.
2. Benefit–Risk Leadership
- Define and execute a data-sharing approach that integrates real-world evidence (RWE) and clinical insights, enhancing:
- Regulatory clarity
- Patient value proposition
- Serve as the primary interface between clinical data and investment decisions.
3. Scientific Leadership
- Shape a personal scientific arbitration framework, contributing to the design of:
- Adaptive trials
- Sub-population-based analysis strategies
- Long-term research agendas.
4. External Representation
- Scientific advisor for Health Authority interactions, ensuring asset presence in:
- Conference discussions
- Regulatory submissions
- Policy positions of high scientific importance.
5. Talent Development
- Lead a culture of excellence by embedding accountability and innovation in your team, promoting strong:
- Inter-functionality
- Cross-cultural collaboration
Why Work Here?
GSK values transparency, respect, and diversity. We cultivate an environment where curiosity and humility drive progress in patient-centric treatment and prevention.
Everyone’s contributions matter
Requirements
Basic Qualifications
Required qualifications and experience:
-
Education:
- Advanced degree (MD, PharmD or Ph.D)
- The ability to lead complex clinical development discussions and governance meetings
-
Experience in Oncology:
- Proven expertise in oncology clinical development, with a robust portfolio of biopharmaceutical and educational experience.
-
Regulatory Biasprudance:
- Full understanding of GCP, ICH, FDA, EMA, NICE, and relevant healthcare regulatory frameworks.
-
Decision-making:
- Demonstrated enterprise-level decision-making experiences, including:
- Portfolio commitment leadership
- Study prioritisation
- Demonstrated enterprise-level decision-making experiences, including:
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Mensuration
Requires a deep industry lens for:
- UNCRAFTED: Securing insights and expertise across all development disciplines.
Why Choose GSK?
GSK is a global biopharmaceutical company determined to unite science, technology, and talent, delivering on a mission: "getting ahead of disease together".
Our Impact
- 4 therapeutic areas: Respiratory, Immunology, Oncology, and Infectious Diseases.
- Commercial scale: GSK’s products and vaccines affect patients and economies globally.
- Career potential: Access to advanced learning and innovation aligned with a resilient culture of high performance.
GSK’s Commitment to You
-
Diverse Opportunities: Career paths and development forums tailored to leaders within:
- Medicinal Strategy
- Regulatory Excellence
- Clinical Science
-
Global Diversity: An active commitment to:
- Inclusion
- Accessibility
- Open dialogue, specifically against historical or social barriers in healthcare.
Check this role against your desired work challenges and goals. Your passionate journey to deliver on the strategic and scientific prerquisites of oncology is April’s gateway!
About Work Arrangement
This hybrid role requires:
- On-site presence at least 2 days/week in one of the posted locations (Cambridge or Waltham, MA; Rockville, MD; San Francisco, CA).
- Options for flexible work on remaining days with collective operational incentives to foster collaboration and knowledge sharing.
Compensation
- Base Salary: $242,250 – $403,750
- Includes a comprehensive benefits package:
- Professional development support
- Bonus structure based on roles and organisational performance
- Long-Term Incentives Program (dependent on individual contribution)
- Health, pension, parental/medical leave, and wellness considerations.
Compensation nuances
Salary ranges reflect factors such as:
- Candidate skill margin
- market rate guidelines
- Education and experience tensors
For salaries outside the US scope, compensation will be subject to discussion during recruitment.
Apply Here
We welcome your application and look forward to partnering with you to shape tomorrow’s oncology. Email your interest, describing:
- How your expertise advances clinical strategy
- How you intend to grow within GSK
Join GSK today and discover an industry where your passion creates solutions that align with medicines.
GSK—Equality and Opportunity
GSK affirms an equal opportunity employer attitude: All candidates will be considered based on skills and proficiency without regard to:
- Racial variation
- Underrepresented communities
- Age/gender beyond position requirements
- Mental and physical ability
- LGBTQ+ alliance
GSK supports an agile working culture across all roles. Speak with the recruitment team to explore tailored hybrid work structures.
Accessibility Request
If you require process adjustments to best demonstrate your strengths during recruitment, please email UKRecruitment.Adjustments@gsk.com.
For further queries unrelated to accessibility rights, use GSK’s Recruitment FAQ tool.
Agency Notice
Only employment businesses that have received explicit prior GSK-issued consent may represent GSK’s recruitment focus. Please refer this notice to GSK’s recruitment strategy team and include search agreements to ensure valid authorization for placing candidates into our process at every step.
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