UK Biobank
IT Systems Engineer - End User Compute

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IT Systems Engineer - End User Compute
IT Engineer (End User Compute)
Application Deadline: 19 July 2026
Department: Data & Technology
Location: Cheadle, based across Park Square and Manchester Science Park
Compensation: £50,000 - £55,000 per year
Help shape the future of end user technology within one of the world's leading health research organisations.
At UK Biobank, technology plays a vital role in enabling world-class health research. Behind every researcher, laboratory, and operational team is a secure, modern digital workplace that allows people to work efficiently, collaborate effectively, and protect some of the world's most valuable health data.
We're looking for an IT Engineer (End User Compute) to join our growing Data & Technology team, helping modernise and secure our end user computing environment as part of a significant technology transformation programme.
This is a fantastic opportunity to take ownership of key technologies, contribute, implement, and mature the future of our Microsoft endpoint estate.
Technical Solutions Architect for IT Security – Key Responsibilities
You will be responsible for:
- Managing, supporting, and improving UK Biobank's End User Compute environment using:
- Microsoft Intune
- Windows Autopilot
- PowerShell
- Microsoft Entra ID in a structured approach to reduce reliance on traditional Active Directory and Group Policy-based device management.
- Supporting endpoint application deployment through:
- Microsoft Intune
- Company Portal
- Patch My PC
- Win32 app packaging
- Related tooling.
- Supporting secure access to internal services via:
- Microsoft Entra Application Proxy
- Global Secure Access
- Zero Trust technologies, enabling a shift away from traditional network or admin access patterns.
- Supporting Microsoft 365 end-user services:
- Windows Remote Desktop Services
- Windows 365
- Azure Virtual Desktop
- AWS EC2/WorkSpaces as part of a secure and modern digital workplace.
- Strengthening End User Compute security:
- Implementing security baselines
- CIS benchmark configurations
- Compliance policies
- Security updates
- Endpoint protection, collaborating with Information Security to continually improve security posture.
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What You’ll Be Doing
If you enjoy delivering technical solutions, solving complex infrastructure challenges, and working with the latest Microsoft technologies, this role offers a genuine opportunity to make an impact.
Requirements
To be successful, you must have:
- Strong knowledge and experience supporting:
- Microsoft Windows 10 & 11
- Apple macOS
- iOS & Android devices.
- Experience managing Microsoft Active Directory, Azure Active Directory/Microsoft Entra ID, Windows Autopilot, compliance policies, and configuration profiles.
- Operational experience supporting:
- End-user devices
- Applications & services within a complex, multi-site organisation.
- Knowledge of security frameworks and best practices such as ISO, NIST, and CIS, with experience in ISO 27001-aligned environments being advantageous.
- Preference will be given to candidates with experience supporting Windows Remote Desktop Services, including:
- Windows 365
- Azure Virtual Desktop
- AWS Virtual Desktop.


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Flexible Working & Location
Working hours are 35 hours per week (Monday to Friday), with flexibility for two days onsite or hybrid working.
About UK Biobank
Our passion for diversity and equality means creating a work environment for all employees that is welcoming, respectful, engaging, and enriched with opportunities for personal and professional development.
We actively welcome applications from:
- People with disabilities
- Long-term health conditions
- Neurodivergent candidates
- Those with diverse thinking styles
If you require adjustments during the recruitment process, please contact Tommy Wilson (jobs@ukbiobank.ac.uk).
Wellbeing at UK Biobank Our Indeed ratings reflect a commitment to employee wellbeing:
- 77% High in employee satisfaction.
- Colleagues often highlight a strong sense of purpose, supportive culture, and opportunities for growth.
Benefits
- 26 days annual leave (+ bank holidays)
- Holiday buy scheme
- Birthday leave
- USS Pension Scheme
- Healthcare cash plan
- Enhanced family leave
- Cycle to Work scheme
- Season ticket loan
- Professional subsidies
- Access to training and development opportunities
- Free on-site gym
- Subsidised canteen lunches
- Free car parking
- Employee discounts portal
- Employee Assistance Programme
- Annual flu vaccination
- Life assurance cover
Early applications are encouraged. The advertised closing date may change due to high volume.
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