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We are looking for a Pharmacometrics Lead, who is innovative and agile to strengthen our Quantitative Clinical Pharmacology group, based at our research site in Slough (UK), Monheim (Germany) or Braine (Belgium).
About the role
Bringing experience in the application of pharmacometrics to pediatric drug development, Neurology and Immunology, with the aspiration to lead/manage more junior staff, to contribute to the teams’ development and grow expertise and skills in these areas.
Who you’ll work with
Reporting to the Global Head of Pharmacometrics, you’ll be leading a team of Pharmacometricians, from both a technical and scientific perspective, to ensure state of the art pharmacometrics approaches are applied to optimize drug discovery and development.
- Working closely with the QCP Leads assigned to the various projects, to ensure clear integration of the pharmacometrics aspects into the programs.
What you’ll do
- Coaching and mentoring junior staff on how to navigate within a project and matrix organization.
- Leading and delivering the Pharmacometrics strategy to support development of our assets. extrapolation (where appropriate), dose selection, trial design, PIP development and ongoing evaluation of data as generated.
- Performing hands-on population PK/PD, exposure-response modeling and clinical trial simulations on an assigned project.
- Developing submission ready fit for purpose Pharmacometrics analysis plans and reports.
- Initiating and overseeing outsourced pharmacometrics activities and further internalizing the work as needed.
- Having a working knowledge about the regulatory pathways on a global basis and opportunities for collaboration with health authorities (either through working parties, advice meetings, and other initiatives) in pediatrics, Neurology and Immunology.
- Promoting MID3 internally and externally.
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Interested?
For this role you’ll need the following education, experience and skills
- Doctorate (PhD or MD) in the related disciplines of Pharmaceutical Sciences, Statistics or Engineering.
- 8+ years (Bio)pharmaceutical industry experience in Pharmacometrics with minimum of 2 years line management responsibilities.
- Hands-on experience in population PK/PD, disease progression modeling, and clinical trial simulations.
- Strong understanding and knowledge of Bayesian methodologies, model-based meta-analyses, PBPK, QSP, and AI/ML in Pharmacometrics.
- Expertise in R, NONMEM or related pharmacometrics software.
Internal applicants should be in their current job for at least 12 months, must meet performance standards and are not on formal corrective/disciplinary process (PIP), warning, final warning, or compliance warning letters within the last 12 months. Please inform your Manager or your Talent Partner before applying to any internal job opportunities.
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At UCB, we’ve embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description, this role is hybrid with 40% of your time spent in the office, irrespective of your current contractual agreement. Should your current working arrangements differ, please contact your Talent Partner to discuss, before submitting your application.
UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Requisition ID: 92356
Recruiter: Joanna Coombs
Hiring Manager: Akash Khandelwal
Talent Partner: Geraldine Beauduin
Job Level: SM II
Please consult HRAnswers for more information on job levels.
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