Principal Investigators (All Levels) - Generative Biology Institute

Key Responsibilities:

To set the research direction for your group and ensuring research activity is consistent with that direction and directly relevant to GBI's vision To recruit and manage a group of outstanding researchers, which may include postdocs, doctoral students (in partnership with the University of Oxford, we are establishing a doctoral programme in Generative Biology with up to 20 fully funded doctoral student positions per year), research assistants and other scientists To mentor highly promising early career researchers to achieve the group's goals and progress their aligned career objectives To collaborate with other groups within GBI and with colleagues within the broader EIT family to deliver bold, ambitious and transformational research that would not be possible within an individual group To help shape the facilities in GBI as part of the scientific strategy for delivering GBI's vision

Requirements

Essential Knowledge, Skills and Experience:

A PhD in a relevant scientific discipline, such as synthetic biology, computational biology and AI, microbial, plant and human cell biology, genomics, robotics and automation, and nucleic acids chemistry A strong publication record in your field, demonstrating the ability to deliver bold, ambitious and transformational advances Track record of building and managing collaborations, both internally and with external academic and/or industry partners, to enhance research capabilities Strong communication and leadership skills, with the ability to engage with senior researchers, technical teams, and external stakeholders We welcome applications from researchers who have experience running their own group as a Professor, Associate Professor, or Assistant Professor, and from those seeking their first independent position. We also actively encourage applications from those who have worked in an commercial setting, such as a biotech and companies leveraging AI for research Assessment of applicants with respect to knowledge skills and experience criteria will be calibrated for career stage

Benefits

Our proposition for our Principal Investigators:

Research groups will be supported by substantial core funding, for posts, consumables, and equipment matched to the needs of the project. Additional posts can be made available to support specific research projects, particularly for ambitious collaborative projects across groups. Group leaders will have the ability to also supervise graduate students and participate in the doctoral program in generative biology being established through the University of Oxford-EIT alliance Access to cutting-edge facilities and infrastructure, initially including mass-spectrometry, flow cytometry, imaging, automation and, sequencing, with intention to expand facilities, in line with GBI's scientific strategy, as we scale Access to significant compute capacity and capability, including in partnership with EIT's AI team Group leaders will be encouraged to publish work from their group Opportunity to translate research with commercial application into a separate company in partnership with GBI's translational team and with financial and operational support from EIT. Where appropriate, we will support applications for faculty appointments at Oxford University, building on the University of Oxford-EIT Alliance

We offer the following benefits:

Globally competitive salary and bonus Pension and travel allowance Training and development opportunities Additional benefits including enhanced holiday pay, life assurance, income protection, private medical insurance, hospital cash plan, therapy services, perk box

Terms of Appointment:

You must be eligible to work in the UK with a willingness to travel as necessary. We are open to sponsoring employment visas for this role; however sponsorship is not available for all visa types or in all circumstances. Eligibility will be assessed on a case-by-case basis You must be based in, or within easy commuting distance of, Oxford During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of our work.

Your application

Please submit a CV (no more than 3 pages, including a list of up to ten key publications), and cover letter explaining why you would like to join GBI (no more than 2 pages)

Please submit a proposal (no more than 5 pages) of the research that you would like to undertake at GBI covering:

The research questions that you would like answer over a 5-10 year period and how this relates to the vision of GBI How this relates to your previous work The challenges that you need to overcome and the resources that you would need in order to be successful How you would intend to partner with colleagues at GBI and with the broader EIT family

We are interested in all research that is consistent with GBI's vision. Some relevant areas include:

Molecular and Cellular Design and Evolution Enzyme design Design of molecular assemblies and machines Experimental accelerated evolution Robotics, automation and autonomous labs Genome mining and informatics-based discovery Computational AI sequence to function Modelling and building genetic and cellular circuits Cellular design Expanding chemistry in biology Nitrogen fixation Carbon fixation Programming cellular assemblies and synthetic tissues Scalable error free DNA and genome synthesis Microbial Genome Synthesis and Design Gb-scale Genome Synthesis for plants, human cells and animals Combinatorial synthetic genomics DNA delivery Predictive models of DNA sequence to function, at the scale of genes and genomes Human health applications and delivery mechanisms

We will be recruiting Principal Investigators over the next 2-3 years, with applications reviewed every one to four months as part of a rolling selection process.