Warman O'Brien
Principal Statistician
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Principal Biostatistician | Global CRO | FSP | Home Based | UK | Europe | Permanent
Our client, a leading global CRO, is seeking an experienced Principal Biostatistician to join a dedicated FSP team, supporting real-world evidence, pharmacoepidemiology, outcomes research, and non-interventional study programmes.
This is an excellent opportunity for a senior statistician with strong real-world data experience to work across impactful studies using electronic health records, claims data, registries, and other real-world data sources. You will provide statistical leadership across non-interventional studies, safety and comparative effectiveness research, and pharmacoepidemiology projects, partnering closely with clients, internal teams, and cross-functional stakeholders.
This position can be home-based across Europe, including UK, Bulgaria, Hungary, Poland, Romania.
What you will be doing:
- Lead statistical activities across real-world evidence, pharmacoepidemiology, and non-interventional studies
- Contribute to and review protocols, statistical analysis plans, and study reports
- Scope, design, and deliver analyses using real-world data sources including EHR, claims, and registries
- Apply pharmacoepidemiologic methods to safety and comparative effectiveness research
- Provide statistical leadership and scientific input to cross-functional teams and clients
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What you will need:
- MSc or PhD in Biostatistics, Statistics, or a related discipline
- 9+ years' biostatistics experience with an MSc, or 7+ years with a PhD
- Strong experience in real-world evidence, pharmacoepidemiology, and non-interventional study methodology
- Proven expertise working with real-world data sources including EHR, claims, and registries
- Strong R programming skills (essential)
- Experience authoring and reviewing protocols and Statistical Analysis Plans (SAPs)
- Solid understanding of biases associated with claims data (particularly US claims) and EHR analyses
- Experience with study designs such as cohort, self-controlled, and target trial emulation studies
- Knowledge of analytical methods including propensity scores, clone-censor-weighting, and time-to-event analyses
- Vaccines and/or infectious disease experience would be advantageous
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What’s in it for you:
- Competitive salary + benefits package including medical, dental, vision, pension, fitness subsidy & life insurance
- Fully home-based across Europe, including UK, Bulgaria, Hungary, Poland, Romania
- Opportunity to work within a dedicated FSP model with a leading global CRO
- Exposure to high-impact real-world evidence, pharmacoepidemiology, and outcomes research studies
- Excellent long-term career development and progression opportunities
What to do next:
If this opportunity is of interest, please apply now with your CV as the organisation is looking to welcome an experienced Principal Biostatistician to the team as soon as possible.
Not what you’re looking for?
Please contact Jo Fornaciari at jo@warmanobrien.com for a confidential discussion about potential other opportunities in the UK and across Europe.
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