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University of Cambridge

Research Associate - Twigger Group (Fixed Term)

Cambridge
Posted 1 day ago
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About The Role

The Cambridge Lactation Laboratory (https://www.cambridgelactationlab.com/) is seeking an enthusiastic and motivated Research Associate to support the Cambridgeshire Multiomics of Milk (CAMB MOM) study.

Join a dynamic and growing research group in the Department of Biochemistry and Pharmacology, under the leadership of Dr. Alecia-Jane Twigger. The team is passionate about women's and infant health and specialises in both experimental (wet lab) and bioinformatic (dry lab) research. Within the group, we will provide you with further training in these disciplines. We also offer the opportunity to undertake 10 days per year of external training programmes to support your career development.

The CAMB MOM study conducts multiomics analyses (lipidomics, metabolomics, proteomics, and transcriptomics) on samples from a cohort of breastfeeding participants in Cambridgeshire. The insights gained from gene-gene interaction networks will be tested using in vitro mammary organoid models and integrated into computational models. By investigating the molecular pathways of human milk production, we aim to resolve breastfeeding challenges and promote optimal long-term health for mothers and infants.

Candidate Requirements

We seek a competent individual with excellent laboratory skills in molecular biology and cell culture. Preferred qualifications include:

  • Previous research experience working with human milk samples
  • Familiarity with in vitro technologies (e.g., tissue culture, 3D organoids, co-cultures).
  • Experience with molecular analysis (e.g. RNA extraction and purification, protein analysis, histology, multiplexed immunostaining, microscopy).

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The ideal candidate will demonstrate responsibility, initiative, independent thinking, and possess excellent communication and organisational skills. Line management experience and the ability to work effectively both individually and within a diverse team are highly desirable.

Key Responsibilities

Supporting Study Sample Collections and Analysis:

  • Organise sample collections with research group members and study participants.
  • Process and store samples for analysis.
  • Coordinate with core facility staff for specialised analysis (e.g., scRNA-sequencing).
  • Collaborate with local and international partners to compare findings across cohorts.

Generate Mammary Organoids In Vitro

  • Optimise human mammary organoid culture conditions
  • Conduct further analyses on cultured cells (e.g., immunofluorescence and genomics).

Laboratory Operations

  • Maintain meticulous records of experiments and develop new SOPs and protocols.
  • Provide day-to-day supervision of undergraduate/postgraduate students where appropriate.

Qualifications

  • Hold a PhD in Biology, Biochemistry, Natural Sciences, or another related field.
  • Practical research experience.

Why Join Us

Being part of the Cambridge Lactation Laboratory, you will have the opportunity to contribute your ideas to ongoing research. You will be able to engage with an opportunity-rich scientific and clinical research environment within the University of Cambridge and nearby Cambridge Biomedical Campus. You will also expand your research network, engaging with the wider international research community. We are committed to fostering an inclusive and supportive environment that promotes intellectual curiosity and scientific excellence. We encourage applications from a diverse group of backgrounds and allow for flexible working hours.

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Fixed-term: The funds for this post are available from 1st August 2026 until 31st July 2027, in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

For informal enquiries, please contact Dr Alecia-Jane Twigger (https://www.bioc.cam.ac.uk/research/faculty/alecia-jane-twigger) via ajt215@cam.ac.uk

For queries regarding the application process, please contact the Biochemistry HR Team via: personnel@bioc.cam.ac.uk

Please quote reference PH50345 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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Skills

Molecular Biology
Cell Culture
In Vitro Technologies
Tissue Culture
3D Organoids
Co-Cultures
RNA Extraction
Protein Analysis
Histology
Multiplexed Immunostaining
Microscopy
Communication Skills
Organisational Skills
Independent Thinking
Team Collaboration

Location

Cambridge, England, United Kingdom

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