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Scientist
Scientist – Drug Metabolism
About Cyprotex
Cyprotex vision is to be pioneers of innovative ADME-Tox partnerships, driving delivery of safer and more effective medicines. With state-of-the-art facilities and technical expertise, we specialise in:
- In vitro and in silico ADME-Tox services
- Assays tailored to client needs including:
- In vitro ADME screening to support discovery
- Regulatory in vitro ADME and DDI (drug-drug interaction) studies
- Specialised mechanistic in vitro human/animal toxicity models
- PBPK/QSAR modelling expertise
- A strong focus on R&D
Our Alderley Park site is set in a stunning 400-acre estate with open green spaces and sweeping viewpoints, easily accessible via public transport to Merseyside, Greater Manchester, Staffordshire, and Shropshire.
Role: Scientist (Drug Metabolism, ADME)
Location & Type
- Location: Alderley Park, Macclesfield, SK10 4TG
- Role Type: Permanent, Full-time (37.5 hrs/week)
Key Responsibilities
- Conduct laboratory-based drug metabolism assays (manual/liquid-handling robotic) under tight deadlines while maintaining high quality
- Analyze and interpret data independently using scientific knowledge
- Take ownership of assay management, including planning, execution, and timeline coordination
- Train colleagues, deliver constructive feedback, and support quality documentation/maintenance
- Continuously identify process/assay improvements and propose solutions
- Assist senior team members in assay development/validation and bespoke project work
- Mentor associate scientists and peers for data analysis/technique execution
- Adhere to safety regulations and quality control procedures
- Monitor/inventory consumables and coordinate with buyers/suppliers
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Skills & Competencies
Essential:
- Ability to organize tasks, meet deadlines, and balance priorities across multiple activities
- Strong troubleshooting/initiative (collaborating with peers as needed)
- Clear verbal/written communication, attention to detail, and cultural collaboration with stakeholders
- Ability to give/receive feedback and apply it constructively
- Experience in liquid-handling robots (e.g., Tecan EVO® platform), LC-MS/MS or LC-ToF-MS data analysis
Requirements
- Degree: MSc or BSc equivalent with laboratory experience (e.g., pharmaceutical industry, biotech, CRO, or academia)
- Essential: Direct experience in in vitro drug metabolism/DDI assays
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Benefits
- Competitive salary and benefits package
- Pension (5% employee contribution, 5% employer contribution*, up to 7.5% for overtime contributions)
- 25 days holiday (plus bank holidays) + annual length-of-service days (up to 30 days total)
- Private health insurance (BUPA coverage for employee/partner/family post-probation)
- Permanent health/dental insurance after qualifying period
- Career progression, training programs, and headcount scheme
- 24/7 wellbeing support and counselling services
- Cycle-to-work scheme, referral bonuses, and additional perks:
- Annual events
- Recognition awards
Onsite Facilities
- Free secure parking
- Restaurant/café & gastro-pub
- Gym, running/walking/cycling routes
- Shuttle bus service for convenience
Note: Évotec fosters Diversity & Inclusion, supporting people in all abilities. Applications from candidates with disabilities are considered equally if qualified.
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