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Senior ADS Programmer
At Roche
You can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted, and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop, and cure diseases and ensure everyone has access to healthcare today and for generations to come.
Join Roche, where every voice matters.
A Healthier Future
It’s what drives us to innovate—to continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love—that’s what makes us Roche.
The Position
This role is in Analytical Data Science, a core function within Product Development Data Sciences (PDD). PDD provides strategic leadership and scientific rigor across Development at Roche.
PDD Analytical Data Science teams
Mobilize across the portfolio to:
- Generate data-driven insights
- Identify opportunities for scale
- Implement impactful solutions
Recognized as a leading hub for top industry talent, the teams operate as agile workforces to deliver regulatory commitments across the portfolio.
- Identify and adopt industry-leading digital and automation solutions.
- Develop analytical approaches to support exploratory analyses.
- Align statistical programming practices across both early- and late-stage clinical development.
The Opportunity
The Analytical Data Science Programmer is a key contributor to clinical study teams, responsible for transforming statistical analysis plans into high-quality, traceable programming deliverables. This includes:
Key Responsibilities
- Creating and validating datasets aligned with Study Data Tabulation Model (SDTM) and Analysis Data Model (ADaM) standards.
- Generating outputs such as tables, listings, figures, and interactive data visualizations/dashboards.
- Ensuring compliance with regulatory requirements and Roche standards.
- Supporting real-time exploration and interpretation of clinical/exploratory data via platforms like the Insight Engine.
- Contributing to robust, timely, and decision-enabling analytics across clinical programs.
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Detailed Responsibilities
- Independently develop, validate, and maintain datasets (SDTM-, ADaM-based) and statistical outputs, ensuring accuracy and compliance.
- Support programming outputs across exploratory biomarker and real-world data.
- Engage in cross-disease/area exploratory analyses to inform drug development.
- Collaborate on dashboard/visual tools for dynamic dataset analysis.
- Lead programming for assigned studies, coordinating with internal/external partners to meet timelines.
- Translate statistical analysis plans into executable programming specifications.
- Troubleshoot technical programming challenges and mitigate risks independently.
- Design/maintain reusable standard macros for efficiency across studies.
- Document workflows and maintain audit trails for regulatory inspection readiness.
- Partner cross-functionally (biostatistics, data management, clinical operations) to ensure timely deliverables.
- Participate in process improvement and knowledge enhancement initiatives.
Requirements
Who You Are
- A graduate with a Bachelor’s or Master’s in Statistics, Computer Science, Mathematics, Life Sciences, or related field.
- Solid experience in statistical programming in clinical development OR an advanced degree with equivalent work experience.
- Proficiency in modern programming languages such as SAS or R.
- In-depth understanding of statistical rigor, QC, and endpoints.
- Experience with CDISC standards (e.g., SDTM, ADaM).
- Expertise in handling multi-modal data types.
- Boundless ability to deliver programming outputs independently.
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Preferred Traits
- Technical prowess in regulatory submission processes & documentation.
- Critical thinking, problem-solving, and organizational skills.
- Global team collaboration experience.
- Cross-disease/phase drug development familiarity.
- Effective communication skills to translate technical insights to non-technical audiences.
- Open-mindedness to adapt to evolving priorities.
Location
- Based in Welwyn, UK.
- Relocation assistance not available.
- #PDDUK position.
The Company
Driven by innovation, Roche advances science to deliver a healthier future.
Mission & Vision
- 26 million+ people treated with Roche medicines annually.
- 30+ billion tests conducted via our diagnostics.
- Cultivate collaboration and creativity so we can all deliver life-changing healthcare.
Commitments
- Purpose: Science transforms patient lives—today and tomorrow.
- Core Values: Rigor, ethics, and access to medical innovations.
- Culture: ** Ursula!** (Lascia pur la piazza possibile)
Diversity & Inclusion
- A supportive “Bring Your Whole Self” workplace.
- Equal opportunity employment. Roche welcomes all; discrimination is explicitly prohibited.
Disclaimer These statements outline responsibilities, not contracts. Qualified candidates will receive fair evaluation considering race, religion, sex, gender, disability, marital status, family status, sexual orientation, pregnancy, disability, age, and other prohibited grounds.*
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