Macclesfield, UK

Are you ready to architect a next-generation Advanced Planning System that unites demand and supply to accelerate clinical medicines to patients? This is a pivotal, hands-on leadership role delivering an integrated, automated planning landscape that transforms how we make decisions and deliver for our pipeline.

You will lead a complex, multi-country programme to design, build, and implement an enterprise-grade APS, automating S&OP/S&OE and embedding robust processes, data, and planning logic across our clinical supply network. You will bring together diverse experts in planning, technology, quality, and data to define the future operating model, including the role of AI and Agentic AI. Can you bring people with you — aligning different voices, building buy-in, and turning bold ideas into adopted practice?

Accountabilities

• APS Strategy and Design — Lead end-to-end design of a fully integrated and automated Advanced Planning System for clinical supply planning, aligned to portfolio and patient delivery outcomes.
• Future-State Operating Model — Define capabilities, roles, and ways of working for the next-generation planning model, including the responsible use of AI/Agentic AI to improve speed, accuracy, and scenario planning.
• Business Requirements to Design — Translate business requirements into system configuration, process design, data structures, and planning logic that scale globally.
• End-to-End Integration — Ensure the solution aligns with end-to-end clinical supply processes from demand signal through manufacturing, packaging, and distribution.
• Governance and Stakeholder Leadership — Run cross-functional programme governance; secure decisions at pace and maintain strong engagement across global teams.
• Standardisation and Data — Drive standardised processes and common data definitions; partner closely with enterprise process owners to embed consistency.
• Compliance and Validation — Lead GxP-compliant validation, testing, and deployment; uphold audit readiness and data integrity.
• Value Realisation — Define clear performance metrics; track benefits in service, cost, risk, and cycle time to demonstrate measurable impact.
• Change and Adoption — Lead change management, communications, and training to ensure sustained adoption and capability uplift.
• Risk and Vendor Management — Anticipate and manage programme risks and issues; lead external vendors to outcomes, quality, and timeline.
• Strategic Contribution — Shape long-term planning and digital strategies, building a platform for continuous improvement.
• Integrated Project Plan — Build and maintain a single, integrated plan that connects scope, schedule, resources, dependencies, and budget.
• Delivery to Time and Budget — Execute with discipline, meeting milestones and financial commitments.
• People Leadership — Provide matrix leadership to a global programme team; develop talent and create a high-performing, mission-focused environment.