BioOrbit
Senior Process Development Scientist
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Senior Process Development Scientist
Company: BioOrbit
Location: London
Type: Full-time
Working Pattern: Hybrid
About BioOrbit
BioOrbit is pioneering space enabled pharmaceutical development. By using microgravity to crystallise biologics and other complex medicines at scale, we aim to open new possibilities in drug formulation, delivery and manufacturing, helping shape how future treatments reach patients worldwide.
Role Overview
We are seeking a Senior Process Development Scientist to lead the translation of lab-scale crystallisation processes into robust, scalable reactor systems. In this role, you will take molecules from early-stage crystallisation through to continuous processing within our crystallisation platform.
You will design and execute experiments to understand and control nucleation and crystal growth. You will work with other bioprocess engineers to translate CFD findings into reactor designs and run DoE to optimise reactor operating conditions. You will integrate PAT tools into the reactor and use the data collected to instruct experiments design.
Key Responsibilities
- Lead the development and scale-up of crystallisation processes for biologic molecules, from early-stage screening through to continuous manufacturing
- Design and execute experiments to understand and control nucleation and crystal growth kinetics
- Apply Design of Experiments (DoE) methodologies to optimise process parameters and define design space
- Translate experimental and modelling insights (e.g. CFD outputs) into reactor design and operating strategies
- Evaluate, implement, and integrate Process Analytical Technology (PAT) tools for real-time monitoring and control
- Analyse complex datasets to drive process understanding, optimisation, and decision-making
- Collaborate closely with mechanical, systems and software engineers to integrate processes into autonomous and flight-ready hardware
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Requirements
- A degree in Chemical Engineering, Chemistry, Biochemical Engineering, Bioengineering or related subject.
- Hands on experience designing, optimising and running bioprocessing equipment
- Experience with biologics (e.g. monoclonal antibodies) and/or crystallisation in an academic or industry setting
- A good technical knowledge of fluid dynamics.
- Demonstrated experience designing and running experiments and interpreting large datasets
Nice to Have
- Familiarity with PAT tools (e.g. FTIR, Raman, imaging probes)
- Exposure to continuous processing or flow reactors
- Experience working in regulated environments (e.g. GMP, GLP) or awareness of regulatory expectations
- Experience working with modelling tools (e.g. CFD) and analytical software (e.g. Python or Minitab)
- Interest in space, microgravity research, or autonomous systems
- Willingness to travel for launch campaigns (up to ~1 month, once per year, currently in Florida)
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Working Arrangements
You will be based at our laboratory in Victoria House (near Holborn station, London). We offer flexible working, with Mondays and Fridays typically available for remote work, though in-person presence will be required as needed.
Why Join BioOrbit
At BioOrbit, you will help build a new field of space-enabled pharmaceutical development. You will join a dynamic team tackling one of the most ambitious challenges in drug development: understanding whether microgravity can unlock new ways to formulate, deliver and manufacture life-saving medicines. As we enter our seed stage phase, you will have significant opportunities to shape our core technology, move quickly from idea to execution and contribute directly to experiments conducted in space.
To Apply
Send your CV and cover letter to info@bioorbit.com
Applications close on 20th August 2026.
Please Note: applications submitted without a cover letter will not be reviewed.
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