Expedeon Inc. (an Abcam company)
Senior Research Associate - High Throughput Screening
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Senior Research Associate - High Throughput Screening
Senior Research Associate – High Throughput Screening
Abcam, one of Danaher’s 15+ operating companies in life sciences, diagnostics, and biotechnology, seeks a Senior Research Associate in our Danaher Affinity Reagent Autonomous Lab (DARAL) in Cambridge, UK. If you’re passionate about innovation that saves lives, let’s bring more to life.
About the Role
At Abcam, we shape the future of cancer research, neurological disorders, infectious diseases, and metabolic disorders by accelerating scientific breakthroughs. Reporting to the Director of Production, you’ll drive impact by leveraging Danaher’s continuous improvement system—turning ideas into tangible solutions for life scientists worldwide.
We thrive in a culture where collaboration and individuality drive progress. As part of a global team of over 1,400 colleagues, you’ll:
- Harness cutting-edge expertise to develop cutting-edge reagents.
- Push boundaries to serve our customers, strengthen scientific excellence, and enhance society.
Learn more about how we achieve this through the Danaher Business System.
Core Responsibilities
The Senior Research Associate – High Throughput Screening delivers antigen-antibody interactions and binding data with precision:
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- Express and purify antibodies (aVHHs, single-domain binders, or other formats) from biosynthesis systems.
- Evaluate and characterise candidate binders’ interactions with their targets via:
- Binding affinity and specificity assays (e.g., ELISA, SPR)
- Biophysical property assessments (e.g., thermal stability, pharmacokinetic profiling)
- Facilitate molecular cloning for optimisation workflows, ensuring seamless integration with screening operations.
Key Requirements
Essential
- Degree: Bachelor’s (BSc) or Master’s (MSc) in life sciences, biochemistry, molecular biology, or a related field.
- Experience (Minimum 2 years) in antibody/protein expression and screening with hands-on expertise in:
- Protein expression (e.g., bacterial, E. coli, or mammalian cells).
- Binder characterisation (ELISA, Surface Plasmon Resonance, or equivalent).
- Purification and assay validation workflows.
- Problem-solving & adaptability: Proven ability to troubleshoot complex lab issues, manage multi-task workflows, and communicate data concisely with cross-functional teams.
Desirable (Optional Pluses)
- Experience in cloning and antibody reformatting (e.g., converting antigen-binding fragments for new formats).
- Hands-on with high-throughput workflows (e.g., liquid handlers, plate-based automation) or standardised documentation systems.
- Knowledge of antibody conjugations or labels (e.g., biotinylation, fluorophore attachment, or radionuclide tagging).
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Why Work with Us?
Joining Abcam’s team means accelerating real-life impact. We empower careers with:
- Global scientific influence: Work on reagents shaping future discoveries in life-threatening diseases.
- Empowering benefits: Comprehensive packages aligned with kinetic rewards, health care, and time-off—see Danaher Benefits Info for details.
- A partnership: We’re dedicated to helping existing and future customers tackle their hard challenges. Together, we create bold solutions—that build a brighter tomorrow.
Ready to Accelerate Your Impact?
We’re recruiting now. Bring your expertise in antibody engineering, screening, and innovation to Cambridge and #BringCamLife to a patient or breakthrough tomorrow.
Apply today at [Link Insert], and together, let’s accelerate life.
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