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Cyprotex

Senior Scientist I (Biologics Design, Production & Characterization)

Alderley Edge
Posted 28 days ago
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We are seeking a highly capable and motivated scientist to join our biologics team. The ideal candidate will bring significant expertise in biologics engineering, design, production and characterization and have a good understanding of biologics drug discovery. Through lab-based leadership, you will be responsible for the execution of multiple discovery and engineering projects. Job Title: Senior Scientist I (Biologics Design, Production and Characterization) Job Type: Permanent Location: Alderley Park, Macclesfield, SK10 4TG Our Company Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and the US. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies Key Accountabilities Design and execution of agreed work plans for biologics engineering, design, production and characterization. Responsible for supporting multiple projects and may be asked to direct internal resources to achieve agreed goals. Will be expected to provide oversight of results to ensure quality to project specifications. Accountable, together with project counterparts, for the design of experiment, review of documentation and client presentations. Will conduct thorough data analysis ahead of product release to internal or external customers. Proposes experimental designs and novel approaches to identify/advance best strategies in addition to planning/ executing project deliverables. Responsible for the implementation of standalone scientific services and deliverables to customers. Where responsible for reports will lead colleagues to co-develop plans for personal growth, aligned to business need. Represent the company at scientific and/or business conferences. Presents and publishes as appropriate peer-reviewed science increasing own and Evotec’s scientific reputation. Knowledge & Experience Strong technical knowledge of biologics discovery and engineering with a proven ability to design and deliver results within agreed timelines and budget, meeting agreed quality criteria. Experience in the design and optimization of expression, purification and characterization workflows to deliver high-quality material and data for complex biologics (e.g. multi-specific antibodies, TCRs). Experience in high throughput methodology with associated data capture and handling. Experience in lead optimization including affinity maturation, humanization and manufacturability. Experience with using in silico-based tools for sequence and structural analysis is desired. Experience of preparing and executing workplans and building trusted partnership with internal and external customers. Requires a track record of leading scientists across specialist fields. Requires a track record of facilitating employee growth through co-development of PDP. Track record of successful problem-solving, high-quality science and influencing of stakeholders and colleagues. Experience of scientific development and research work ideally with publications in a relevant scientific field. Education and Qualifications Ideally a Ph.D. degree or corresponding experience in a relevant scientific discipline with relevant experience within industry. Alternatively, a relevant first degree and several years additional experience in drug discovery. Evotec Leadership Competencies Active Communication: Communicates actively, working on further clarity and responsiveness Constructive Feedback: Actively seeks and provides constructive feedback, using it to improve processes and outcomes Consistent Team Engagement: Engages frequently, fostering a more positive and collaborative environment Foundational Direction Sharing: Communicates pragmatic directions, leading to general understanding and alignment Occasional Planning: Begins anticipating problems and improves on proactively taking precautions Effective Delegation: Delegates tasks effectively, trusting team members to handle responsibilities and providing necessary support and development Benefits Package Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%. 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days Private health insurance with BUPA for the employee and their partner/family under the company scheme Well being support 24/7 and counselling services Permanent health insurance provides 75% of the base salary after the qualifying period Private dental cover, on completion (but not subject to) of your 3-month probationary period Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit. Career progression within the company, we have excellent training and support and continuing professional development opportunities Cycle-to-work scheme Refer a friend scheme, team and annual events, recognition awards and many more! Onsite Facilities The company pays for secure onsite parking Restaurant, Café, and Gastro pub Gym and workout studio, running, walking, and cycling routes Good public transport links with the shuttle bus service. Please note closing date for all applications will be Thursday 9th July 2026 We may close this earlier depending on the number of applications received FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap. ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities. Established in 1999, Cyprotex has over 150 staff based at its sites in the UK (Alderley Park in Cheshire) and in the USA (Watertown, MA). We operate as a contract research organisation and we have over 1700 customers worldwide within industries such as the pharmaceutical, cosmetics and personal care and the chemical and agrichemical markets. Outstanding customer service excellence and quality are key focuses of the business. In addition to our customer projects, we invest heavily in Research and Development of new techniques – many of these projects are exploring new in vitro or in silico methods to understand how chemicals or new pharmaceuticals may behave in humans in terms of their safety or efficacious effects. Cyprotex is a growing and successful business and we are constantly recruiting for motivated and hardworking staff who thrive within a dynamic and vibrant organisation. We are committed to providing an environment where employees can learn and develop their skills and are recognised and rewarded for the contribution they make to the Company. Much of our work is performed in multi-disciplinary project teams that enables exchange of ideas and knowledge, enabling people to develop and take on additional responsibility either within the team or across teams in the business. Please click on the link below to access and review our Privacy Information for Applicants: Privacy Information for Applicants

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Skills

Biologics Engineering
Biologics Design
Protein Production
Biologics Characterization
Drug Discovery
Expression Optimization
Purification Workflows
High Throughput Methodology
Lead Optimization
Affinity Maturation
Humanization
Manufacturability
In Silico Analysis
Project Leadership
Data Analysis
Stakeholder Management

Location

Alderley Edge, England, United Kingdom

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