MitoRx Therapeutics
Senior Scientist Medicinal Chemistry (Maternity cover)
How your CV stacks up
Upload your CV to see how well it fits this job role
?%
Company Description
MitoRx is developing new treatments to restore healthy mitochondrial metabolism in patients living with high-risk obesity. Our first-in-class small molecule asset, MTRX31, targets the elimination of ectopic fat from affected organs in people with metabolically unhealthy obesity, by restoring mitochondrial health rather than suppressing appetite. This approach has the potential to deliver durable and higher quality weight loss, lower the risk of cardiovascular complications and other serious diseases, and improve quality of life.
MitoRx offers a science‑driven, collaborative environment for professionals interested in translating cutting‑edge mitochondrial biology into meaningful clinical impact.
Role Description
MitoRx is looking for a Senior Scientist in Medicinal Chemistry to join us on a fixed-term basis, covering maternity leave from approximately August / September 2026 to May 2027. This is a fantastic opportunity for an experienced medicinal chemist to step into a pivotal, hands-on role at the heart of our drug discovery programme — working closely with our R&D team, CRO partners, and DMPK vendors to keep our chemistry moving forward at pace.
Reasons to use Rodeo
Start with a chat, not a search bar
Grad scheme, placement, apprenticeship? Not sure what you want yet — that's fine. Your agent talks it through with you and turns "I have no idea" into a shortlist.
It searches the market for you
Every day your agent scans the market matching roles against what actually matters to you, not just keywords on a CV.
Only hits
No noise. No "maybe this fits." Just roles with a clear explanation of why they're right — and where to focus when applying.
This is a largely remote role, but requires travel to Oxford / Cambridge / London at least one day per month.
Key Responsibilities:
Management of Chemistry CROs:
- Supervise the synthesis progress and update management internally
- Quality Control of synthesized compounds including the purity minimum as requested and analytical data supports proposed structures
- Ensure timelines are adhered to
- Capture and file appropriately experimental and analytical data in CCD vault.
R&D weekly meeting organization:
- Prepare the Agenda
- Update meeting documents, such as Action and Decision logs, on Sharepoint.
Management of corporate compounds and data management system:
- Management of corporate compound registry system and inventory (including registering of compounds on CDD Vault and Bioascent Inventory)
- File appropriately DMPK data in CCD vault.
- Management of the logistics of compounds (efficient shipment from/to CROs and MitoRx lab)
Get help with your application
Your very own career expert that helps elevate your application to the next level.
Support med chem group objectives and activities:
- Assist in chemistry and ADME service providers selection
- Co-managing of DMPK vendors and update on results management internally
- Work with consultants to develop appropriate study protocols
- Raise PO and appropriate file management of quotations and POs
- Support future MitoRx Patent filings.
Qualifications
- Masters or ideally PhD in organic chemistry or similar, with a strong knowledge of analytic techniques (i.e. 1H,13C-NMR, LCMS).
- Minimum of two years’ experience in pharmaceutical, biotechnology and/or CRO environments, ideally small/medium size, in a similar Medicinal Chemist role.
- Proactivity and problem-solving skills.
- Ability to work independently as well as part of a team.
- Strong communication skills, both written and verbal.
For more information and applications, please email careers@mitorxtherapeutics.com with your CV and a covering letter quoting the job title of the vacancy.
“It took my CV and asked me questions relevant to understanding what kind of jobs to suggest for me. Suggestions were almost perfect. Jobs were exactly what I’ve been looking for.”
Jessica, London
Skills
Location